ArticleEuropean radiology2020
Increased tortuosity of basilar artery might be associated with higher risk of aneurysm development.
Article in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 18 citations in OpenAlex.
- Associations between middle cerebral artery tortuosity, aneurysm wall enhancement, and hemodynamics assessed by four-dimensional-flow and high-resolution magnetic resonance imaging.Neuroradiology · 2026Article
- Automated segmentation and quantitative analysis of vascular curvature features in unruptured intracranial aneurysms based on time-of-flight magnetic resonance angiography (TOF-MRA).Quantitative imaging in medicine and surgery · 2026Article
- Accurate and fully automated diameter measurements of Circle of Willis arteries on MRA imaging.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025Article
- Discrepancy in vessel tortuosity measurements of anterior circulation cerebral artery between digital subtraction angiography and magnetic resonance angiography.Journal of cerebrovascular and endovascular neurosurgery · 2025Article
- Effect of Siphon Morphology on the Risk of C7 Segment Aneurysm Formation : A Case-control CFD Study.Clinical neuroradiology · 2024Article
- An Improved Path-Finding Method for the Tracking of Centerlines of Tortuous Internal Carotid Arteries in MR Angiography.Journal of imaging · 2024Article
- Statistical shape representation of the thoracic aorta: accounting for major branches of the aortic arch.Computer methods in biomechanics and biomedical engineering · 2023Article
- Morphology of middle cerebral artery using computed tomography angiographic study in a tertiary care hospital.Anatomy & cell biology · 2023Article
- Effects of Path-Finding Algorithms on the Labeling of the Centerlines of Circle of Willis Arteries.Tomography (Ann Arbor, Mich.) · 2023Article
- How Cerebral Vessel Tortuosity Affects Development and Recurrence of Aneurysm: Outer Curvature versus Bifurcation Type.Journal of stroke · 2021Article
- Determination of patient prognosis based on unruptured basilar artery aneurysm morphology using a novel dynamic prediction model.Frontiers in neurologyArticle
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
objectivesWe analysed tortuosity of basilar artery (BA) to determine its relationship with the presence of aneurysm.
methodsWe retrospectively analysed 71 patients with BA aneurysms along with 71 age- and risk factors-matched control patients without BA aneurysm. From patients' medical records, we obtained their history including previous and current diseases and medications. For each patient, we calculated relative length (RL), sum of angle metrics (SOAM), triangular index (TI), product of angle distance (PAD) and inflexion count metrics (ICM). We used t-test and Mann-Whitney U test for continuous variables and χ
resultsWe found significant positive correlation between age and SOAM (R = 0.195, p = 0.02) and PAD (R = 0.199, p = 0.018). Our study also showed that patients with BA aneurysm had significantly higher SOAM (0.21 ± 0.16 vs. 0.11 ± 0.08; p < 0.01), PAD (0.30 ± 0.19 vs. 0.18 ± 0.11; p < 0.01), TI (0.23 ± 0.23 vs. 0.10 ± 0.16; p < 0.01) and ICM (0.20 ± 0.16 vs. 0.15 ± 0.11; p = 0.045). In multivariate logistic regression analysis, after adjustment for all possible confounders, SOAM (OR = 1.086; 95% CI 1.046-1.136; p < 0.01) and TI (OR = 1.004; 95%C: 1.002-1.006; p < 0.01) remained independently associated with higher risk of BA aneurysm.
conclusionsIncreased tortuosity of BA is associated with higher risk of its aneurysm development. KEY POINTS: • Basilar artery sum of angle metrics and product of angle distance are correlated with age. • Basilar artery tortuosity is independently associated with higher risk of its aneurysm development. • Basilar artery tortuosity is positively correlated with its diameter and bifurcation angle.
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