ReviewWorld journal of pediatrics : WJP2021
Advance in the understanding of vasovagal syncope in children and adolescents.
Review in World journal of pediatrics : WJP, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Guidelines for the diagnosis and treatment of neurally mediated syncope in children and adolescents (revised 2024).World journal of pediatrics : WJP · 2024Guideline
- Difference in clinical characteristics between functional syncope and vasovagal syncope in children.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- The Correlation and Predictive Value of Prognostic Nutrition Index with Vasovagal Syncope in Children.Pediatric cardiology · 2026Article
- Co-segregation ofFrontiers in pediatrics · 2026Article
- Long-Term Prognosis and Impact Factors of Metoprolol Treatment in Children with Vasovagal Syncope.Biomedicines · 2025Article
- Features of Clinical Manifestations and Heart Rate Variability in Children with Malignant Vasovagal Syncope.Children (Basel, Switzerland) · 2025Article
- Missed or Delayed Diagnosis of Heart Disease by the General Pediatrician.Children (Basel, Switzerland) · 2025Review
- Roles of Single Nucleotide Polymorphisms in the SLC6A2 Gene in the Risk of Vasovagal Syncope Among Children in Eastern China: A Case-Control Study.Health science reports · 2025Article
- Advances in diagnosis, management, and long-term outcomes of pediatric vasovagal syncope: a comprehensive review.Frontiers in cardiovascular medicine · 2025Review
- Nomogram Based on HRV for Predicting the Therapeutic Effects of Orthostatic Training in Children with Vasovagal Syncope.Children (Basel, Switzerland) · 2024Article
- Predictive value of Tpeak-Tend interval of supine and orthostatic electrocardiogram in the diagnosis between psychogenic pseudosyncope and vasovagal syncope in children.Scientific reports · 2024Article
- Serum uric acid predicts therapeutic response to midodrine hydrochloride in children with vasovagal syncope: a pilot study.European journal of pediatrics · 2024Article
- Value of catecholamine levels in the differential diagnosis of vasovagal syncope and psychogenic pseudosyncope in children.Frontiers in pediatrics · 2024Article
- Application of mind map can promote the health education effect of children with vasovagal syncope.Frontiers in cardiovascular medicine · 2023Article
- Development of prognostic nomogram model to predict syncope recurrence in children with vasovagal syncope.Frontiers in cardiovascular medicine · 2023Article
- Predictive analysis of catecholamines and electrolytes for recurrence of orthostatic intolerance in children.Frontiers in pediatrics · 2023Article
- The value of QT interval in differentiating vasovagal syncope from epilepsy in children.Italian journal of pediatrics · 2022Article
- Research progress on the predictive value of electrocardiographic indicators in the diagnosis and prognosis of children with vasovagal syncope.Frontiers in cardiovascular medicine · 2022Review
- Spectrum of underlying diseases in syncope and treatment of neurally-mediated syncope in children and adolescents over the past 30 years: A single center study.Frontiers in cardiovascular medicine · 2022Article
- Poincaré Plot Can Be a Useful Tool to Select Potential Responders to Metoprolol Therapy in Children with Vasovagal Syncope.International journal of general medicine · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVasovagal syncope (VVS) accounts for 60-80% of cases of neurally mediated syncope. VVS results from acute orthostatic intolerance and recurrent syncopal attacks, which can seriously affect an individual's quality of life. In addition, some children even experience trauma during attacks. Therefore, it is particularly important to clarify the pathogenesis of VVS. The aim of our study is to reveal the latest research progress of VVS. DATA SOURCES: Literature that involved the pathogenesis of VVS were selected from Cochrane Library (1990-2019), EMBASE (1991-2019) and PubMed (1968-2019) databases.
resultsHypovolemia, autonomic dysfunction, vasomotor dysfunction, baroreceptor reflex abnormalities, endothelial dysfunction, serotonin surges, and gut microbiota were involved in the underlying mechanism of VVS.
conclusionsVVS is not always a benign prognosis. Various aspects were involved in its pathogenesis. Bezold-Jarish reflex, dysfunction of the autonomic nervous system, genetic factors and so on played important roles in VVS; however, the mechanism remains unclear.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.