Evidence map›Paper›PMID 32405646›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2021

Cognitive Functions Predict Trajectories of Sleepiness Over 10 Years: A Population-Based Study.

Ann D Cohen, Yichen Jia, Stephen Smagula, Chung-Chou H Chang, Beth Snitz, Sarah B Berman, Erin Jacobsen, Mary Ganguli

Open access · greenAbstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  3. Sleep, Sleepiness, and Memory.Sleep science (Sao Paulo, Brazil) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ann D CohenDepartment of Psychiatry, School of Medicine, University of Pittsburgh, Pennsylvania.
Yichen JiaDepartment of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pennsylvania.
Stephen SmagulaDepartment of Psychiatry, School of Medicine, University of Pittsburgh, Pennsylvania.
Chung-Chou H ChangDepartment of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pennsylvania.
Beth SnitzDepartment of Neurology, School of Medicine, University of Pittsburgh, Pennsylvania.
Sarah B BermanDepartment of Neurology, School of Medicine, University of Pittsburgh, Pennsylvania.
Erin JacobsenDepartment of Psychiatry, School of Medicine, University of Pittsburgh, Pennsylvania.
Mary GanguliDepartment of Psychiatry, School of Medicine, University of Pittsburgh, Pennsylvania.
University of Pittsburgh · US

Funding

Mild Cognitive Impairment: A Prospective Community StudyR01AG023651 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GANGULI, MARY · 2005 to 2020
$27.1M
Mild Cognitive Impairment: A Prospective Community StudyR37AG023651 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Carmen Andreescu, MARY GANGULI · 2021 to 2026
$18.2M
Depression in dementia caregivers: Linking brain structure and sleep-wake risksK01MH112683 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SMAGULA, STEPHEN F · 2017 to 2021
$875k
NIA NIH HHS R01 AG023651NIA NIH HHS R37 AG023651NIMH NIH HHS K01 MH112683
6 · The paper itself

Abstract

backgroundExcessive daytime sleepiness is associated with chronic disorders of aging and mortality. Because longitudinal data are limited on the development of sleep disturbances and cognitive changes in older adults, we investigated the demographic, clinical, and cognitive predictors of self-reported daytime sleepiness over a period of 10 years.

methodsWe jointly modeled latent trajectories over time of sleepiness, cognitive domains, and informative attrition and then fit models to identify cognitive trajectories and baseline characteristics that predicted the trajectories of sleepiness.

resultsThree latent trajectory groups were identified: emerging sleepiness, persistent sleepiness, and consistently low daytime sleepiness accounting for attrition in all groups. Compared with low sleepiness, emerging sleepiness was significantly associated with declining attention and subjective memory complaints; persistent sleepiness was associated with lower baseline scores in all cognitive domains, declining language trajectory, and more subjective memory complaints.

conclusionsThese findings suggest that persistent sleepiness and emerging daytime sleepiness are associated with cognitive decline and multiple morbidities, albeit more subtly in emerging daytime sleepiness. Furthermore, these data suggest that change in the cognitive domain of attention and subjective memory complaints may be early indicators of future sleep disturbance.

Indexed as

AgedAttentionCognitive DysfunctionCohort StudiesDisorders of Excessive SomnolenceExecutive FunctionFemaleHumansMaleMemorySelf ReportSleepinessTime FactorsCognitionCognitive agingSleep

Identifiers

PMID32405646
PMCPMC7907493
OpenAlexW3026549893

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.