ReviewOpen forum infectious diseases2020
In Full Flow: Left Ventricular Assist Device Infections in the Modern Era.
Review in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06039176 (Human/Machine Interface), which is not on this map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
Who cites it
29 citing papers in PubMed, 67 citations in OpenAlex.
- Material-Driven Clinical Complications in Mechanical Circulatory Support: From Blood-Material Interactions to Device-Related Adverse Events.Materials (Basel, Switzerland) · 2026Review
- Driveline Infections in Durable LVAD Support: Risk Factors, Microbiology, and Resistance Patterns from a Large Cohort.Diagnostics (Basel, Switzerland) · 2026Article
- Perioperative management and outcomes of hip and knee arthroplasty among heartmate 3 left ventricular assist device recipients.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- Article
- Review
- Infections in mechanical circulatory support.Frontiers in cardiovascular medicine · 2026Review
- Perioperative clinical profiles and longitudinal outcomes in patients supported by continuous-flow left ventricular assist devices: a comprehensive analysis of early and late follow-up data.Frontiers in cardiovascular medicine · 2026Article
- Article
- Local Infections Associated with Ventricular Assist Devices: Materials-Related Challenges and Emerging Solutions.Materials (Basel, Switzerland) · 2025Review
- Comparative Outcomes FollowingOpen forum infectious diseases · 2025Article
- Exploratory analysis of long-term suppressive therapy with dalbavancin in ventricular assist device infections caused by Staphylococcus aureus.Scientific reports · 2025Article
- Article
- Epidemiology and impact of device-specific infections on patients receiving left ventricular assist devices.JHLT open · 2025Article
- Phage Therapy for Cardiac Implantable Electronic Devices and Vascular Grafts: A Targeted Literature Review.Pathogens (Basel, Switzerland) · 2024Review
- The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024Article
- Pre-Implant Immune Status is Associated with Infection Risk After Left Ventricular Assist Device Implantation.Journal of inflammation research · 2024Article
- Iron Deficiency in Patients with Left Ventricular Assist Devices.Cardiac failure review · 2024Review
- A Case Report of a LVAD Driveline Infection Diagnosed by Point-of-care Ultrasound.Clinical practice and cases in emergency medicine · 2023Article
- Body mass index-dependent immunological profile changes after left ventricular assist device implantation.Frontiers in immunology · 2023Article
- Left ventricular assist device-related infections and the risk of cerebrovascular accidents: a EUROMACS study.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With the rising prevalence of heart disease in the United States, there is increasing reliance on durable mechanical circulatory support (MCS) to treat patients with end-stage heart failure. Left ventricular assist devices (LVADs), the most common form of durable MCS, are implanted mechanical pumps that connect to an external power source through a transcutaneous driveline. First-generation LVADs were bulky, pulsatile pumps that were frequently complicated by infection. Second-generation LVADs have an improved design, though infection remains a common and serious complication due to the inherent nature of implanted MCS. Infections can affect any component of the LVAD, with driveline infections being the most common. LVAD infections carry significant morbidity and mortality for LVAD patients. Therefore, it is paramount for the multidisciplinary team of clinicians caring for these patients to be familiar with this complication. We review the epidemiology, prevention, diagnosis, treatment, and outcomes of LVAD infections.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.