Evidence map›Paper›PMID 32405413›Full record

ArticleAnnals of medicine and surgery (2012)2020

Prophylactic effects of biogenic selenium nanoparticles on acute toxoplasmosis: An in vivo study.

Mojtaba Shakibaie, Fatemeh Ezzatkhah, Esraa Gabal, Ebrahim Badparva, Sareh Jahanbakhsh, Hossein Mahmoudvand

Open access · diamondAbstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

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  6. Potent In Vitro and In Vivo Effects ofTropical medicine and infectious disease · 2023
    Article
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  10. The role ofFrontiers in cellular and infection microbiology · 2023
    Article
  11. Review
  12. Review
  13. Review
  14. In vitro and in vivo Anti-Infection and drug resistance · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Mojtaba ShakibaiePharmaceutical Sciences and Cosmetic Products Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Fatemeh EzzatkhahDepartment of Laboratory Sciences, Sirjan School of Medical Sciences, Sirjan, Iran.
Esraa GabalAgricultural Science and Resource Management in the Tropics and Subtropics, Bonn University, Germany.
Ebrahim BadparvaRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Sareh JahanbakhshStudent Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.
Hossein MahmoudvandRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Lorestan University of Medical Sciences · IRKerman University of Medical Sciences · IRSirjan University of Technology · IRUniversity of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this investigation, the in vivo efficacy and safety of biogenic selenium nanoparticles (SeNPs) are assessed against acute toxoplasmosis caused by

methodsMale NMRI mice were orally treated with normal saline (control group) and SeNPs at the doses of 5 and 10 mg/kg once a day for 14 days

resultsThe rate of mortality in the infected mice receiving SeNPs at the doses of 5 and 10 mg/kg compared with the mice in the control group was 100% on the 9 and 10 days after the administration. The mean number of tachyzoites in the infected mice receiving SeNPs was significantly lower than that in the control group. No significant difference (

conclusionFindings of the present investigation showed the considerable efficacy of SeNPs with no important toxicity for curing acute toxoplasmosis in the mice model. However, further studies are needed to clarify the accurate anti-Toxoplasma mechanisms of SeNPs.

Indexed as

ProphylacticSeleniumToxicityToxoplasma gondiiTreatment

Identifiers

PMID32405413
PMCPMC7212177
OpenAlexW3023655536

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.