ArticleIranian journal of basic medical sciences2020
Chronic consumption of cassava juice induces cellular stress in rat substantia nigra.
Article in Iranian journal of basic medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Integrative Analysis of Transcriptomics and Metabolomics Reveals the Effects of Western-Style Diets on Spleen Function.Biology · 2025Article
- Female naturalists and the patterns of suppression of women scientists in history: the example of Maria Sibylla Merian and her contributions about useful plants.Journal of ethnobiology and ethnomedicine · 2023Article
- Effects of Cassava Juice (Toxins · 2020Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesCassava ( MATERIALS AND
methodsMale Wistar rats were administered cassava juice daily (3.57 g/kg and 28.56 g/kg,
resultsChronic administration of cassava juice, or linamarin, increased motor impairment. The rats that received 28.56 g/kg cassava showed increased MDA-4-HAD content in SNpc and nitrite levels in NE with respect to controls. Significant loss of TH-IR in SNpc, NE, and NA was not found. The 28.56 g/kg cassava administration produced dopaminergic atrophy and microgliosis, whereas linamarin induced hypertrophy and C3-related apoptosis in SNpc.
conclusionCCC induces cellular stress on dopaminergic neurons, which could contribute to motor impairment in the rat.
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Registered trials
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