Evidence map›Paper›PMID 32405339›Full record

ArticleOncotarget2020

Distinct pattern of one-carbon metabolism, a nutrient-sensitive pathway, in invasive breast cancer: A metabolomic study.

Jéssica Reis Santos, Dan Linetzky Waitzberg, Ismael Dale Cotrim Guerreiro da Silva, Tharcisio Citrangulo Tortelli Junior, Luciana Rodrigues Carvalho Barros, Gisele André Baptista Canuto, Andréa Tedesco Faccio, Lydia Fumiko Yamaguchi, Massuo Jorge Kato, Marina Franco Maggi Tavares and 4 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Jéssica Reis SantosGastroenterology Department, University of São Paulo School of Medicine (FMUSP), São Paulo, Brazil.
Dan Linetzky WaitzbergGastroenterology Department, University of São Paulo School of Medicine (FMUSP), São Paulo, Brazil.
Ismael Dale Cotrim Guerreiro da SilvaGynecology Department, College of Medicine of the Federal University of São Paulo (EPM-UNIFESP), São Paulo, Brazil.
Tharcisio Citrangulo Tortelli JuniorCentro de Investigação Translacional em Oncologia (LIM24), Departamento de Radiologia e Oncologia, Faculdade de Medicina da Universidade de São Paulo and Instituto do Câncer do Estado de São Paulo, São Paulo, Brazil.
Luciana Rodrigues Carvalho BarrosCentro de Investigação Translacional em Oncologia (LIM24), Departamento de Radiologia e Oncologia, Faculdade de Medicina da Universidade de São Paulo and Instituto do Câncer do Estado de São Paulo, São Paulo, Brazil.
Gisele André Baptista CanutoDepartamento de Química Analítica, Instituto de Química, Universidade Federal da Bahia, Salvador, Brazil.
Andréa Tedesco FaccioDepartamento de Química Fundamental, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.
Lydia Fumiko YamaguchiDepartamento de Química Fundamental, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.
Massuo Jorge KatoDepartamento de Química Fundamental, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.
Marina Franco Maggi TavaresDepartamento de Química Fundamental, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.
Ana Cristina MartinezGastroenterology Department, University of São Paulo School of Medicine (FMUSP), São Paulo, Brazil.
Ângela Flavia LogulloGynecology Department, College of Medicine of the Federal University of São Paulo (EPM-UNIFESP), São Paulo, Brazil.
Raquel Suzana M M TorrinhasGastroenterology Department, University of São Paulo School of Medicine (FMUSP), São Paulo, Brazil.
Graziela RavacciGastroenterology Department, University of São Paulo School of Medicine (FMUSP), São Paulo, Brazil.
Universidade de São Paulo · BRUniversidade Federal de São Paulo · BRInstituto do Câncer do Estado de São Paulo · BRUniversidade Federal da Bahia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Altered cell metabolism is a hallmark of cancer and critical for its development. Particularly, activation of one-carbon metabolism in tumor cells can sustain oncogenesis while contributing to epigenetic changes and metabolic adaptation during tumor progression. We assessed whether increased one-carbon metabolism activity is a metabolic feature of invasive ductal carcinoma (IDC). Differences in the metabolic profile between biopsies from IDC (

Indexed as

invasive ductal carcinomaone-carbon metabolismtargeted metabolomicstumor metabolismuntargeted metabolomics

Identifiers

PMID32405339
PMCPMC7210010
OpenAlexW3022322349

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.