Evidence map›Paper›PMID 32405254›Full record

ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2020

Real-time PCR-based SARS-CoV-2 detection in Canadian laboratories.

Jason J LeBlanc, Jonathan B Gubbay, Yan Li, Robert Needle, Sandra Radons Arneson, Dionne Marcino, Hugues Charest, Guillaume Desnoyers, Kerry Dust, Ramzi Fattouh and 19 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
3.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 148 citations in OpenAlex.

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  12. SARS-CoV-2 seroprevalence in Nova Scotia blood donors.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024
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  16. Prospective, clinical comparison of self-collected throat-bilateral nares swabs and saline gargle compared to health care provider collected nasopharyngeal swabs among symptomatic outpatients with potential SARS-CoV-2 infection.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024
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18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 12 institutions in 1 country.

Jason J LeBlancDivision of Microbiology, Department of Pathology and Laboratory Medicine, Nova Scotia Health Authority (NSHA), Room 404B, MacKenzie Building, 5788 University Avenue, Halifax, Nova Scotia B3H 1V8, Canada; Departments of Pathology, Medicine, and Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada. Electronic address: jason.leblanc@nshealth.ca.
Jonathan B GubbayDepartment of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Public Health Ontario Laboratories, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.
Yan LiNational Microbiology Laboratory (NML), Public Health Agency of Canada (PHAC), Winnipeg, Manitoba, Canada.
Robert NeedlePublic Health and Microbiology Laboratory, St. John's, Newfoundland, Canada.
Sandra Radons ArnesonNational Microbiology Laboratory (NML), Public Health Agency of Canada (PHAC), Winnipeg, Manitoba, Canada.
Dionne MarcinoNational Microbiology Laboratory (NML), Public Health Agency of Canada (PHAC), Winnipeg, Manitoba, Canada.
Hugues CharestLaboratoire De Santé Publique Du Québec/INSPQ, Sainte-Anne-de-Bellevue, Quebec, Canada.
Guillaume DesnoyersCentre Hospitalier Universitaire Dr. Georges L. Dumont, Moncton, New-Brunswick, Canada.
Kerry DustCadham Provincial Laboratory, Winnipeg, Manitoba, Canada.
Ramzi FattouhDepartment of Laboratory Medicine, St. Michael's Hospital, Toronto, Ontario, Canada.
Richard GarceauCentre Hospitalier Universitaire Dr. Georges L. Dumont, Moncton, New-Brunswick, Canada.
Gregory GermanQueen Elizabeth Hospital, Charlottetown, Prince Edward Island, Canada.
Todd F HatchetteDivision of Microbiology, Department of Pathology and Laboratory Medicine, Nova Scotia Health Authority (NSHA), Room 404B, MacKenzie Building, 5788 University Avenue, Halifax, Nova Scotia B3H 1V8, Canada; Departments of Pathology, Medicine, and Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada.
Robert A KozakDepartment of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Sunnybrook Research Institute, Toronto, Ontario, Canada.
Mel KrajdenPublic Health Laboratory, British Columbia Centre for Disease Control (BCCDC), Vancouver, British Columbia, Canada.
Theodore KuschakNational Microbiology Laboratory (NML), Public Health Agency of Canada (PHAC), Winnipeg, Manitoba, Canada.
Amanda L S LangRoy Romanow Provincial Laboratory (RRPL), Saskatchewan Health Authority (SHA), Regina, Saskatchewan, Canada.
Paul LevettPublic Health Laboratory, British Columbia Centre for Disease Control (BCCDC), Vancouver, British Columbia, Canada.
Tony MazzulliDepartment of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Department of Microbiology, Mount Sinai Hospital, Toronto, Ontario, Canada.
Ryan McDonaldRoy Romanow Provincial Laboratory (RRPL), Saskatchewan Health Authority (SHA), Regina, Saskatchewan, Canada.
Samira MubarekaDepartment of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Sunnybrook Research Institute, Toronto, Ontario, Canada.
Natalie PrystajeckyPublic Health Laboratory, British Columbia Centre for Disease Control (BCCDC), Vancouver, British Columbia, Canada.
Candy RutherfordSt Joseph's Healthcare, Hamilton, Ontario, Canada.
Marek SmiejaSt Joseph's Healthcare, Hamilton, Ontario, Canada.
Yang YuPublic Health and Microbiology Laboratory, St. John's, Newfoundland, Canada.
George ZahariadisPublic Health and Microbiology Laboratory, St. John's, Newfoundland, Canada.
Nathan ZelyasDivision of Microbiology, Department of Pathology and Laboratory Medicine, Nova Scotia Health Authority (NSHA), Room 404B, MacKenzie Building, 5788 University Avenue, Halifax, Nova Scotia B3H 1V8, Canada; Provincial Laboratory for Public Health (ProvLab), Calgary, Alberta, Canada.
Nathalie BastienNational Microbiology Laboratory (NML), Public Health Agency of Canada (PHAC), Winnipeg, Manitoba, Canada.
COVID-19 Pandemic Diagnostics Investigation Team of the Canadian Public Health Laboratory Network (CPHLN) Respiratory Virus Working Group
Public Health Agency of Canada · CABC Centre for Disease Control · CASt. John’s Health Sciences Centre · CADalhousie University · CADr. Georges-L.-Dumont University Hospital Centre · CASaskatchewan Health Authority · CASt. Joseph’s Healthcare Hamilton · CASunnybrook Health Science Centre · CAToronto Public Health · CAInstitut National de Santé Publique du Québec · CAMount Sinai Hospital · CASt. Michael's Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With emergence of pandemic COVID-19, rapid and accurate diagnostic testing is essential. This study compared laboratory-developed tests (LDTs) used for the detection of SARS-CoV-2 in Canadian hospital and public health laboratories, and some commercially available real-time RT-PCR assays. Overall, analytical sensitivities were equivalent between LDTs and most commercially available methods.

Indexed as

PandemicsBetacoronavirusCanadaClinical Laboratory TechniquesCoronavirus InfectionsCOVID-19COVID-19 TestingCOVID-19 VaccinesHumansLaboratoriesLimit of DetectionPneumonia, ViralReal-Time Polymerase Chain ReactionSARS-CoV-2COVID-19 VaccinesCoronavirusCOVID-19MolecularNAATPCRSARS-CoV-2

Identifiers

PMID32405254
PMCPMC7219382
OpenAlexW3025007192

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.