Evidence map›Paper›PMID 32404980›Full record

Trial reportScientific reports2020

Proteomic profiles before and during weight loss: Results from randomized trial of dietary intervention.

Sylwia M Figarska, Joseph Rigdon, Andrea Ganna, Sölve Elmståhl, Lars Lind, Christopher D Gardner, Erik Ingelsson

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01826591 (Do Insulin Secretion or Genotype Pattern Predict Low Fat vs Low Carb Weight Loss Success?), which is not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01826591 nacompletednot on this map

Do Insulin Secretion or Genotype Pattern Predict Low Fat vs Low Carb Weight Loss Success?

TypeinterventionalSponsorStanford UniversityRan2013 to 2016Enrolled609ConditionsObesity, Insulin ResistanceArmsLow-Carbohydrate Diet, Low-Fat Diet, Mobile App
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Screening for Circulating Inflammatory Proteins Does Not Reveal Plasma Biomarkers of Constant Tinnitus.Journal of the Association for Research in Otolaryngology : JARO · 2023
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Sylwia M FigarskaDepartment of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Joseph RigdonQuantitative Sciences Unit, Stanford University School of Medicine, Palo Alto, CA, 94304, USA.
Andrea GannaProgram in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Sölve ElmståhlDepartment of Clinical Sciences, Division of Geriatric Medicine, Lund University, Malmö University Hospital, Malmö, Sweden.
Lars LindDepartment of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden.
Christopher D GardnerStanford Diabetes Research Center, Stanford, CA, 94305, USA. cgardner@stanford.edu.
Erik IngelssonDepartment of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Stanford University · USUppsala University · SEBroad Institute · USLund University · SE

Funding

Stanford Center for Clinical & Translational Education and Research (Spectrum)UL1TR003142 · NCATS · STANFORD UNIVERSITY · PI O'HARA, RUTH M · 2019 to 2023
$45.0M
NCATS NIH HHS UL1 TR003142
6 · The paper itself

Abstract

Inflammatory and cardiovascular biomarkers have been associated with obesity, but little is known about how they change upon dietary intervention and concomitant weight loss. Further, protein biomarkers might be useful for predicting weight loss in overweight and obese individuals. We performed secondary analyses in the Diet Intervention Examining The Factors Interacting with Treatment Success (DIETFITS) randomized intervention trial that included healthy 609 adults (18-50 years old) with BMI 28-40 kg/m

Indexed as

Diet, ReducingProteomeProteomicsWeight LossAgedBiomarkersBody Mass IndexCross-Sectional StudiesEarly Medical InterventionFemaleHumansMaleMiddle AgedObesityBiomarkersProteome

Identifiers

PMID32404980
PMCPMC7220904
OpenAlexW3025113689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.