Evidence map›Paper›PMID 32404896›Full record

ArticleSpinal cord series and cases2020

Clinical features of coronavirus disease 2019 (COVID-19) in a cohort of patients with disability due to spinal cord injury.

Miguel Rodríguez-Cola, Irena Jiménez-Velasco, Francisco Gutiérrez-Henares, Elisa López-Dolado, Claudia Gambarrutta-Malfatti, Eduardo Vargas-Baquero, Ángel Gil-Agudo

Abstract read
In one paragraph

Article in Spinal cord series and cases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Perceived impact of the COVID-19 pandemic among people with spinal cord injury: A descriptive study.Archives of rehabilitation research and clinical translation · 2023
    Article
  7. Article
  8. Living With Cervical Spinal Cord Injury During the COVID-19 Pandemic: A Qualitative Study.Archives of rehabilitation research and clinical translation · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Towards a sensitive and accurate interpretation of molecular testing for SARS-CoV-2: a rapid review of 264 studies.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2021
    Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. The COVID-19 pandemic and people with disability.Disability and health journal · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miguel Rodríguez-ColaDepartment of Internal Medicine, Hospital Nacional de Parapléjicos de Toledo, Toledo, Spain.
Irena Jiménez-VelascoDepartment of Internal Medicine, Hospital Nacional de Parapléjicos de Toledo, Toledo, Spain.
Francisco Gutiérrez-HenaresDepartment of Rehabilitation, Hospital Nacional de Parapléjicos de Toledo, Toledo, Spain.
Elisa López-DoladoDepartment of Rehabilitation, Hospital Nacional de Parapléjicos de Toledo, Toledo, Spain.ORCID http://orcid.org/0000-0002-3358-727X
Claudia Gambarrutta-MalfattiDepartment of Internal Medicine, Hospital Nacional de Parapléjicos de Toledo, Toledo, Spain.
Eduardo Vargas-BaqueroDepartment of Rehabilitation, Hospital Nacional de Parapléjicos de Toledo, Toledo, Spain.
Ángel Gil-AgudoDepartment of Rehabilitation, Hospital Nacional de Parapléjicos de Toledo, Toledo, Spain. amgila@sescam.jccm.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designCohort study of patients with spinal cord injury (SCI).

objectivesTo describe the clinical and analytical features of a coronavirus disease 2019 (Covid-19) infected cohort with SCI to enable accurate diagnosis and to outline prevention measures.

settingThis study was conducted at the National Hospital for Paraplegics (Toledo, Spain).

methodsA cohort analysis of seven patients with SCI infected by Covid-19 was performed. Diagnosis was confirmed with reverse transcriptase polymerase chain reaction (RT-PCR) of nasal exudate or sputum samples. Clinical, analytical, and radiographic findings were registered.

resultsRT-PCR detected COVID-19 infection in all patients, affecting males and people with a cervical level of injury more often (five out of seven). The average delay for diagnostic confirmation was 4 days (interquartile range, 1-10). Fever was the most frequent symptom (six out of seven). The second most common symptom was asthenia (four out of seven), followed by dyspnea, cough, and expectoration (three out of seven for each symptom). The Modified Early Warning System score for Covid-19 severity rating was classified as severe in five out of seven cases. All but one patient showed radiological alterations evident in chest X-rays at the time of diagnosis. All patients recovered gradually.

conclusionOur patients with SCI and Covid-19 infection exhibited fewer symptoms than the general population. Furthermore, they presented similar or greater clinical severity. The clinical evolution was not as pronounced as had been expected. This study recommends close supervision of the SCI population to detect early compatible signs and symptoms of Covid-19 infection.

Indexed as

BetacoronavirusAdultAgedCohort StudiesCoronavirus InfectionsCOVID-19FemaleHumansMaleMiddle AgedPandemicsPersons with DisabilitiesPneumonia, ViralRisk FactorsSARS-CoV-2Spain

Identifiers

PMID32404896
PMCPMC7220608

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.