ArticleScientific reports2020
Oxytocin and bone quality in the femoral neck of rats in periestropause.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Risk factors of osteoporosis in post-gastrectomy gastric cancer patients: a systematic review and meta-analysis.Scientific reports · 2026Pooled it
- Role of Oxytocin in Obesity.Current diabetes reports · 2026Review
- Periestropause enhances hypoxia-induced panic and microglial remodelling without altering respiratory control.Journal of neuroendocrinology · 2026Article
- The microarchitecture and chemical composition of the femur neck of senescent female rats after different physical training protocols.GeroScience · 2024Article
- Role of oxytocin in bone.Frontiers in endocrinology · 2024Review
- The Effect of Oxytocin on Osteoporosis Improvement: A Systematic Review.Medical journal of the Islamic Republic of Iran · 2024Review
- Association between Serum Oxytocin, Bone Mineral Density and Body Composition in Chinese Adult Females.Medicina (Kaunas, Lithuania) · 2022Article
- Oxytocin and Related Peptide Hormones: Candidate Anti-Inflammatory Therapy in Early Stages of Sepsis.Frontiers in immunology · 2022Review
- Oxytocin and Bone: Review and Perspectives.International journal of molecular sciences · 2021Review
- Telmisartan Prevents Alveolar Bone Loss by Decreasing the Expression of Osteoclasts Markers in Hypertensive Rats With Periodontal Disease.Frontiers in pharmacology · 2020Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study is to identify whether oxytocin (OT) contributes to the reduction of osteopenia in the femoral neck of rats in periestropause. Animals in irregular estrous cycles received two NaCl injections (0.15 mol/L) or OT (134 μg/kg) over a 12-h interval, and after thirty-five days without treatments, the biological sample collection was performed. The oxytocin group (Ot) demonstrated the highest enzymatic activity of alkaline phosphatase (p = 0.0138), lowest enzymatic activity of tartrate-resistant acid phosphatase (p = 0.0045), higher percentage of compact bone (p = 0.0359), cortical expression of runt-related transcription factor 2 (p = 0.0101), osterix (p = 0.0101), bone morphogenetic protein-2/4 (p = 0.0101) and periostin (p = 0.0455). Furthermore, the mineral-to-matrix ratio (ν
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.