Evidence map›Paper›PMID 32404792›Full record

ArticleMenopause (New York, N.Y.)2020

Dairy intake is not associated with improvements in bone mineral density or risk of fractures across the menopause transition: data from the Study of Women's Health Across the Nation.

Taylor C Wallace, Shinyoung Jun, Peishan Zou, George P McCabe, Bruce A Craig, Jane A Cauley, Connie M Weaver, Regan L Bailey

Open access · hybridAbstract read
In one paragraph

Article in Menopause (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  6. Dairy products and bone health.Aging clinical and experimental research · 2022
    Review
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Taylor C WallaceDepartment of Nutrition and Food Studies, George Mason University, Fairfax, VA.
Shinyoung JunDepartment of Nutrition Science, Purdue University, West Lafayette, IN.
Peishan ZouDepartment of Nutrition Science, Purdue University, West Lafayette, IN.
George P McCabeDepartment of Statistics, Purdue University, West Lafayette, IN.
Bruce A CraigDepartment of Statistics, Purdue University, West Lafayette, IN.
Jane A CauleyDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, PA.
Connie M WeaverWeaver and Associates Consulting, LLC, West Lafayette, IN.
Regan L BaileyDepartment of Nutrition Science, Purdue University, West Lafayette, IN.
Purdue University West Lafayette · USGeorge Mason University · USUniversity of Pittsburgh · US

Funding

The Study of Women's Health Across the Nation (SWAN): The Impact of Midlife and the Menopause Transition on Health and Functioning in Early Old AgeU19AG063720 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Maria Mori Brooks · 2020 to 2026
$61.3M
Development of a Total Nutrient IndexU01CA215834 · NCI · TEXAS A&M AGRILIFE RESEARCH · PI REGAN BAILEY, JANET A. TOOZE · 2017 to 2026
$2.2M
NCI NIH HHS U01 CA215834NIA NIH HHS U19 AG063720
6 · The paper itself

Abstract

objectiveMenopause represents a period in which bone deterioration is accelerated; thus, primary prevention strategies to address age-related bone loss are crucial. Dairy products contain more than a dozen essential nutrients, including calcium, phosphorus, vitamin D, and high-quality protein, as well as bioactive compounds that may promote bone mineralization. However, the relationship between dairy consumption and bone health across the menopause transition remains largely unknown. The purpose of this analysis was to estimate the change in lumbar spine and femoral neck bone mineral density and the risk of bone fracture by the frequency of dairy intakes among women across the menopausal transition using the publicly available data from the Study of Women's Health Across the Nation.

methodsWe analyzed total dairy foods in four categories of <0.5, 0.5 to <1.5, 1.5 to <2.5, and ≥2.5 servings/d or <1.5 and ≥1.5 servings/d. A general linear model was used to estimate the association of dairy intake with the 10-year bone mineral density loss rate and a linear mixed model was used to estimate the annualized bone mineral density loss rate of the femoral neck and lumbar spine. A Cox proportional hazard model was applied to calculate hazard ratios and 95% confidence intervals of the nontraumatic fractures. Poisson regression was used to determine the relative risks and 95% confidence intervals of the nontraumatic fractures. The models were controlled for race/ethnicity, age, height, weight, smoking status, physical activity, alcohol consumption, calcium use, menopausal status, and total caloric intake.

resultsNo significant differences in bone mineral density change were observed, regardless of baseline menopausal status. No significant differences in the risk of nontraumatic fracture were observed.

conclusionsIn this group of US women undergoing the menopausal transition, dairy food intake was neither associated with femoral and spine bone mineral density loss nor the risk of fractures.

Indexed as

Bone DensityFractures, BoneDairy ProductsFemaleHumansMenopauseWomen's Health

Identifiers

PMID32404792
PMCPMC7386862
OpenAlexW3025524707

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.