ArticleScience translational medicine2020
PET ligands [
Open access · greenAbstract read
In one paragraph
Article in Science translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Radiopharmaceuticals for PET and SPECT Imaging: A Literature Review over the Last Decade.International journal of molecular sciences · 2022Pooled it
- Cross-talk between glycosylation pathways: Mechanistic insights and implications for human diseases.Molecular metabolism · 2026Review
- Radiosynthesis and evaluation of a carbon-11 labeled PET ligand for imaging of O-GlcNAcase.American journal of nuclear medicine and molecular imaging · 2025Article
- Studying the O-GlcNAcome of human placentas using banked tissue samples.Glycobiology · 2024Article
- Gas Phase Transformations in Carbon-11 Chemistry.International journal of molecular sciences · 2024Review
- Review
- Understanding and exploiting the roles of O-GlcNAc in neurodegenerative diseases.The Journal of biological chemistry · 2023Review
- Development of a Novel [ACS chemical neuroscience · 2023Article
- Chemical Biology Approaches to Understanding Neuronal O-GlcNAcylation.Israel journal of chemistry · 2023Article
- Tandem Mass Spectrometry as an Independent Method for Corroborating Fluorine-18 Radioactivity Measurements in Positron Emission Tomography.ACS measurement science au · 2022Article
- PET Molecular Imaging in Drug Development: The Imaging and Chemistry Perspective.Frontiers in medicine · 2022Review
- Region- and voxel-based quantification in human brain of [EJNMMI research · 2021Article
- Synthesis of [ACS chemical neuroscience · 2021Article
- Recent developments on PET radiotracers for TSPO and their applications in neuroimaging.Acta pharmaceutica Sinica. B · 2021Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors at 5 institutions in 3 countries.
Shuiyu LuMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room B3C346, 10 Center Drive, Bethesda, MD 20892-1003, USA.ORCID 0000-0003-0310-4318
Mohammad B HaskaliMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room B3C346, 10 Center Drive, Bethesda, MD 20892-1003, USA.ORCID 0000-0003-3084-2084
Kevin M RuleyEli Lilly and Co, Indianapolis, IN 46285, USA.
Nicolas J-F DreyfusEli Lilly and Co, Windlesham GU20 6PH, UK.
Susan L DuBoisEli Lilly and Co, Indianapolis, IN 46285, USA.
Soumen PaulMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room B3C346, 10 Center Drive, Bethesda, MD 20892-1003, USA.
Jeih-San LiowMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room B3C346, 10 Center Drive, Bethesda, MD 20892-1003, USA.
Cheryl L MorseMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room B3C346, 10 Center Drive, Bethesda, MD 20892-1003, USA.
Aneta KowalskiMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room B3C346, 10 Center Drive, Bethesda, MD 20892-1003, USA.
Robert L GladdingMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room B3C346, 10 Center Drive, Bethesda, MD 20892-1003, USA.
Jeremy GilmoreEli Lilly and Co, Windlesham GU20 6PH, UK.ORCID 0000-0003-2551-5839
Adrian J MoggEli Lilly and Co, Windlesham GU20 6PH, UK.ORCID 0000-0001-7712-2450
S Michelle MorinEli Lilly and Co, Indianapolis, IN 46285, USA.
Peter J Lindsay-ScottEli Lilly and Co, Windlesham GU20 6PH, UK.
J Craig RubleEli Lilly and Co, Indianapolis, IN 46285, USA.ORCID 0000-0002-9551-1529
Nancy A KantEli Lilly and Co, Indianapolis, IN 46285, USA.
Sergey ShcherbininEli Lilly and Co, Indianapolis, IN 46285, USA.
Vanessa N BarthEli Lilly and Co, Indianapolis, IN 46285, USA.
Michael P JohnsonEli Lilly and Co, Indianapolis, IN 46285, USA.ORCID 0000-0001-6164-3569
Maria CuadradoLilly, S. A. Avenida de la Industria 30, 28108 Alcobendas, Madrid, Spain.
Enrique JambrinaLilly, S. A. Avenida de la Industria 30, 28108 Alcobendas, Madrid, Spain.
Andrew J MannesDepartment of Perioperative Medicine, Clinical Center, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892-1510, USA.ORCID 0000-0001-5834-5667
Hugh N NuthallEli Lilly and Co, Windlesham GU20 6PH, UK.
Sami S ZoghbiMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room B3C346, 10 Center Drive, Bethesda, MD 20892-1003, USA.
Cynthia D JesudasonEli Lilly and Co, Indianapolis, IN 46285, USA.
Robert B InnisMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room B3C346, 10 Center Drive, Bethesda, MD 20892-1003, USA.
Victor W PikeMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room B3C346, 10 Center Drive, Bethesda, MD 20892-1003, USA. pikev@mail.nih.gov.ORCID 0000-0001-9032-2553
National Institute of Mental Health · USEli Lilly (United States) · USEli Lilly (United Kingdom) · GBEli Lilly (Spain) · ESNational Institutes of Health Clinical Center · US
Funding
PET Radiopharmaceutical SciencesZIAMH002793 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PIKE, VICTOR W · 2009 to 2025
$69.8MClinical Evaluation of PET RadiotracersZIAMH002852 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI INNIS, ROBERT · 2009 to 2025
$48.6MTranslational Evaluation Of PET RadiotracersZIAMH002795 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI INNIS, ROBERT · 2009 to 2025
$32.0MIntegrative And Molecular Studies Of Pain And Pain ControlZIACL090033 · CLC · CLINICAL CENTER · PI MANNES, ANDREW · 2014 to 2025
$0kIntramural NIH HHS ZIA MH002793Intramural NIH HHS ZIA MH002795Intramural NIH HHS ZIA MH002852
Abstract
We aimed to develop effective radioligands for quantifying brain
Indexed as
beta-N-AcetylhexosaminidasesHydrolasesAnimalsBrainGlucosamineLigandsPositron-Emission TomographyRatsbeta-N-AcetylhexosaminidasesGlucosamineHydrolasesLigands
Identifiers
What OpenQuestion holds
Textmetadata
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.