Evidence map›Paper›PMID 32404502›Full record

ArticleStroke and vascular neurology2020

Comparison of carotid atherosclerotic plaques between subjects in Northern and Southern China: a Chinese atherosclerosis risk evaluation study.

Dandan Yang, Yang Ji, Dan Wang, Hiroko Watase, Daniel S Hippe, Xihai Zhao, Chun Yuan

Registry-linked trialOpen access · goldAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Stroke and vascular neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02017756 (A Phase II Study of Chinese Atherosclerosis Risk Evaluation), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02017756 unknown statusnot on this map

A Phase II Study of Chinese Atherosclerosis Risk Evaluation: Investigation of Carotid Atherosclerotic Disease in Patients With Ischemic Cerebrovascular Events

TypeobservationalSponsorTsinghua UniversityRan2012 to 2014Enrolled1,000ConditionsIschemic Stroke, Transient Ischemic Attack, Carotid Atherosclerotic Disease
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Dandan Yang *Center for Brain Disorders Research, Capital Medical University and Beijing Institute of Brain Disorders, Beijing, China.ORCID 0000-0002-6528-0846
Yang Ji *Department of Radiology, Fourth Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Dan WangDepartment of Radiology, Fourth Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Hiroko WataseDepartment of Surgery, University of Washington, Seattle, Washington, USA.
Daniel S HippeDepartment of Radiology, University of Washington, Seattle, Washington, USA.
Xihai ZhaoCenter for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University School of Medicine, Tsinghua University, Beijing, China xihaizhao@tsinghua.edu.cn.
Chun YuanDepartment of Radiology, University of Washington, Seattle, Washington, USA.
University of Washington · USHarbin Medical University · CNCapital Medical University · CNTsinghua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeTo investigate differences in the characteristics of carotid atherosclerotic plaques of symptomatic subjects in northern and southern China using MRI.

methodsSixty-three subjects in northern China (mean age: 59.1±8.6 years, 45 men) and 56 subjects in southern China (mean age: 60.4±8.6 years, 38 men) were included. All subjects underwent carotid artery multicontrast vessel wall MRI. Plaque morphology, calcification, lipid-rich necrotic core, intraplaque haemorrhage, luminal surface disruption and high-risk plaque were measured and identified. All plaque characteristics were compared between subjects in northern and southern China using Mann-Whitney U test or χ

resultsCompared with subjects in southern China, those in northern China had significantly greater areas for lumen (57.7±14.9 mm

conclusionSubjects in northern China have significantly larger vessel size and may have a higher prevalence of vulnerable plaques than those in southern China. Our findings provide additional perspective to optimise the management of cerebrovascular disease in individuals in different regions in China. TRIAL REGISTRATION NUMBER: NCT02017756.

Indexed as

Magnetic Resonance ImagingPlaque, AtheroscleroticAgedCarotid ArteriesCarotid Artery DiseasesChinaCross-Sectional StudiesFemaleFibrosisHemorrhageHumansMaleMiddle AgedNecrosisPredictive Value of TestsPrevalencearteryatherosclerosisMRIplaque

Identifiers

PMID32404502
PMCPMC7337372
OpenAlexW3003662806

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.