Evidence map›Paper›PMID 32404475›Full record

ArticleJournal of clinical pathology2020

High methionyl-tRNA synthetase expression predicts poor prognosis in patients with breast cancer.

Qin Jin, Gang Liu, Biao Wang, Shubin Li, Kan Ni, Chunyu Wang, Jingyu Ren, Shu Zhang, Yanfeng Dai

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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  11. High expression of VARS promotes the growth of multiple myeloma cells by causing imbalance in valine metabolism.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Qin Jin *Department of Pathology, Affiliated Hospital of Nantong University, Nantong, China.
Gang Liu *College of Life Science, Inner Mongolia University, Hohhot, Inner Mongolia, China.ORCID http://orcid.org/0000-0002-5180-3765
Biao Wang *College of Life Science, Inner Mongolia University, Hohhot, Inner Mongolia, China.
Shubin LiCollege of Life Science, Inner Mongolia University, Hohhot, Inner Mongolia, China.
Kan NiDepartment of Thyroid and Breast Surgery, Affiliated Hospital of Nantong University, Nantong, China.
Chunyu WangCollege of Life Science, Inner Mongolia University, Hohhot, Inner Mongolia, China.
Jingyu RenCollege of Life Science, Inner Mongolia University, Hohhot, Inner Mongolia, China.
Shu ZhangDepartment of Pathology, Affiliated Hospital of Nantong University, Nantong, China daiyf@life.imu.edu.cn tdfyzs@163.com.
Yanfeng DaiCollege of Life Science, Inner Mongolia University, Hohhot, Inner Mongolia, China daiyf@life.imu.edu.cn tdfyzs@163.com.
Inner Mongolia University · CNNantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsMethionyl-tRNA synthetase (MARS) is known to play a critical role in initiating translation and protection against cellular damages in vivo. The aim of this study was to clarify the role of MARS in breast cancer (BC) progression.

methodsThe expressions of

resultsThe expression level of

conclusionsHigh expression level of MARS in the human BC tissues was significantly associated with the unfavourable prognosis of patients with BC, suggesting that MARS may serve as a potential prognostic marker for the clinical diagnosis and prognostic prediction of BC.

Indexed as

AdultAgedAged, 80 and overBiomarkers, TumorBreast NeoplasmsFemaleHumansMethionine-tRNA LigaseMiddle AgedPrognosisBiomarkers, TumorMARS1 protein, humanMethionine-tRNA Ligasebreast cancerdiagnosticstumour angiogenesistumour markers

Identifiers

PMID32404475
PMCPMC7691814
OpenAlexW3024541456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.