Evidence map›Paper›PMID 32404426›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Chloroplast Sec14-like 1 (CPSFL1) is essential for normal chloroplast development and affects carotenoid accumulation in

José G García-Cerdán, Eva M Schmid, Tomomi Takeuchi, Ian McRae, Kent L McDonald, Nichakarn Yordduangjun, Ahmed M Hassan, Patricia Grob, C Shan Xu, Harald F Hess and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. VIA1 is a conserved regulator of thylakoid membrane integrity that acts through VIPP1.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  19. A Sec14 domain protein is required for photoautotrophic growth and chloroplast vesicle formation inProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

José G García-CerdánHoward Hughes Medical Institute, University of California, Berkeley, CA 94720; jggarcia.cerdan@gmail.com niyogi@berkeley.edu.ORCID 0000-0002-5561-0629
Eva M SchmidDepartment of Bioengineering, University of California, Berkeley, CA 94720.
Tomomi TakeuchiMichigan State University-Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, MI 48824.ORCID 0000-0002-2976-6902
Ian McRaeDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720-3102.
Kent L McDonaldElectron Microscope Laboratory, University of California, Berkeley, CA 94720.
Nichakarn YordduangjunDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720.ORCID 0000-0002-8049-122X
Ahmed M HassanMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.
Patricia GrobHoward Hughes Medical Institute, University of California, Berkeley, CA 94720.ORCID 0000-0002-8330-8961
C Shan XuJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147.ORCID 0000-0002-8564-7836
Harald F HessJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147.ORCID 0000-0003-3000-1533
Daniel A FletcherDepartment of Bioengineering, University of California, Berkeley, CA 94720.ORCID 0000-0002-1890-5364
Eva NogalesHoward Hughes Medical Institute, University of California, Berkeley, CA 94720.ORCID 0000-0001-9816-3681
Krishna K NiyogiHoward Hughes Medical Institute, University of California, Berkeley, CA 94720; jggarcia.cerdan@gmail.com niyogi@berkeley.edu.ORCID 0000-0001-7229-2071
Howard Hughes Medical Institute · USUniversity of California, Berkeley · USLawrence Berkeley National Laboratory · USMichigan State University · US

Funding

Plant Biotechnology for Health and SustainabilityT32GM110523 · NIGMS · MICHIGAN STATE UNIVERSITY · PI LAST, ROBERT LOUIS · 2014 to 2023
$2.2M
Howard Hughes Medical InstituteNIGMS NIH HHS T32 GM110523
6 · The paper itself

Abstract

Plastid isoprenoid-derived carotenoids serve essential roles in chloroplast development and photosynthesis. Although nearly all enzymes that participate in the biosynthesis of carotenoids in plants have been identified, the complement of auxiliary proteins that regulate synthesis, transport, sequestration, and degradation of these molecules and their isoprenoid precursors have not been fully described. To identify such proteins that are necessary for the optimal functioning of oxygenic photosynthesis, we screened a large collection of nonphotosynthetic (acetate-requiring) DNA insertional mutants of

Indexed as

CarotenoidsChlamydomonas reinhardtiiChloroplastsPhotosynthesisPhylogenyPlant ProteinsProtein DomainsCarotenoidsPlant ProteinscarotenoidsCRAL-TRIO domainphosphatidic acidphotosynthesisphytoene

Identifiers

PMID32404426
PMCPMC7275715
OpenAlexW3025723801

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.