Evidence map›Paper›PMID 32404352›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

TRIM14 Is a Key Regulator of the Type I IFN Response during

Caitlyn T Hoffpauir, Samantha L Bell, Kelsi O West, Tao Jing, Allison R Wagner, Sylvia Torres-Odio, Jeffery S Cox, A Phillip West, Pingwei Li, Kristin L Patrick and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 59 citations in OpenAlex.

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  15. The balance between antiviral and antibacterial responses duringbioRxiv : the preprint server for biology · 2024
    Article
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  19. Identification of KeyInternational journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Caitlyn T HoffpauirDepartment of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, Bryan, TX 77807.
Samantha L BellDepartment of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, Bryan, TX 77807.ORCID 0000-0002-5453-3203
Kelsi O WestDepartment of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, Bryan, TX 77807.ORCID 0000-0002-9632-7205
Tao JingDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77807; and.ORCID 0000-0003-1936-4392
Allison R WagnerDepartment of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, Bryan, TX 77807.ORCID 0000-0002-6592-3741
Sylvia Torres-OdioDepartment of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, Bryan, TX 77807.
Jeffery S CoxDepartment of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA 94720.
A Phillip WestDepartment of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, Bryan, TX 77807.ORCID 0000-0003-2884-6895
Pingwei LiDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77807; and.ORCID 0000-0002-1815-3107
Kristin L PatrickDepartment of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, Bryan, TX 77807.ORCID 0000-0003-2442-4679
Robert O WatsonDepartment of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, Bryan, TX 77807; robert.watson@tamu.edu.ORCID 0000-0003-4976-0759
Texas A&M Health Science Center · USTexas A&M University · USUniversity of California, Berkeley · US

Funding

The role of Listeria cyclic-di-AMP during infection and immunityP01AI063302 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI PORTNOY, DANIEL A · 2004 to 2025
$45.5M
Host-Directed Strategies to Create Synergistic Antibacterial TherapiesDP1AI124619 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COX, JEFFERY S · 2015 to 2019
$3.9M
Discovery of novel, ubiquitin-regulated mechanisms of TB control by macrophagesR01AI120694 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COX, JEFFERY S, KROGAN, NEVAN J · 2015 to 2019
$3.3M
Pre-mRNA splicing regulation is critical for controlling macrophage activationR35GM133720 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Kristin Leigh Patrick · 2019 to 2026
$3.3M
Molecular basis of viral DNA sensing through the cGAS-STING pathwayR01AI145287 · NIAID · TEXAS A&M AGRILIFE RESEARCH · PI Pingwei Li · 2019 to 2026
$2.5M
TRIM proteins polarize DNA sensing outcomes during the innate immune response to Mycobacterium tuberculosisR01AI125512 · NIAID · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI WATSON, ROBERT OWEN · 2016 to 2019
$1.5M
NIAID NIH HHS DP1 AI124619NIAID NIH HHS P01 AI063302NIAID NIH HHS R01 AI120694NIAID NIH HHS R01 AI125512NIAID NIH HHS R01 AI145287NIGMS NIH HHS R35 GM133720
6 · The paper itself

Abstract

Tripartite motif-containing proteins (TRIMs) play a variety of recently described roles in innate immunity. Although many TRIMs regulate type I IFN expression following cytosolic nucleic acid sensing of viruses, their contribution to innate immune signaling and gene expression during bacterial infection remains largely unknown. Because

Indexed as

AnimalsCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseDisease Models, AnimalGene Expression RegulationGene Knockout TechniquesHEK293 CellsHumansInterferon Type IIntracellular Signaling Peptides and ProteinsMacrophagesMembrane ProteinsMiceMycobacterium tuberculosisNitric Oxide Synthase Type IINucleotidyltransferasesPhosphorylationcGAS protein, humanCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseInterferon Type IIntracellular Signaling Peptides and ProteinsMembrane ProteinsNitric Oxide Synthase Type IINos2 protein, mouseNucleotidyltransferasesProtein Serine-Threonine KinasesReceptor, Interferon alpha-betaRecombinant ProteinsStat3 protein, mouseSTAT3 Transcription FactorSting1 protein, mouseSTING ProteinTBK1 protein, humanTbk1 protein, mouseTrim14 protein, mouseTripartite Motif Proteins

Identifiers

PMID32404352
PMCPMC7313415
OpenAlexW3024270774

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.