Evidence map›Paper›PMID 32404189›Full record

ReviewEuropean journal of medical research2020

The role of passive immunization in the age of SARS-CoV-2: an update.

Johannes C Fischer, Kurt Zänker, Martijn van Griensven, Marion Schneider, Detlef Kindgen-Milles, Wolfram Trudo Knoefel, Artur Lichtenberg, Balint Tamaskovics, Freddy Joel Djiepmo-Njanang, Wilfried Budach and 10 more

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in European journal of medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Review
  5. Article
  6. Review
  7. Article
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  11. Low ADAMTS13 Activity Correlates with Increased Mortality in COVID-19 Patients.TH open : companion journal to thrombosis and haemostasis · 2021
    Article
  12. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 4 countries.

Johannes C FischerInstitute for Transplant Diagnostics and Cell Therapeutics, Heinrich Heine University, Düsseldorf, Germany.
Kurt ZänkerThe Nanjing Han & Zaenker Cancer Institute, Nanjing and Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing Tech University, Jiangsu, China.
Martijn van GriensvenMERLN Institute for Technology-Inspired Regenerative Medicine, Department cBITE, Maastricht University, Maastricht, The Netherlands.
Marion SchneiderDepartment of Experimental Anesthesiology, University of Ulm, Ulm, Germany.
Detlef Kindgen-MillesDepartment of Anesthesiology and Intensive Care Medicine, Heinrich Heine University, Düsseldorf, Germany.
Wolfram Trudo KnoefelDepartment of Surgery, Heinrich Heine University, Düsseldorf, Germany.
Artur LichtenbergDepartment of Cardiac Surgery, Heinrich Heine University, Düsseldorf, Germany.
Balint TamaskovicsDepartment of Radiation Oncology, Heinrich Heine University, Moorenstr. 5, 40225, Düsseldorf, Germany.
Freddy Joel Djiepmo-NjanangDepartment of Radiation Oncology, Heinrich Heine University, Moorenstr. 5, 40225, Düsseldorf, Germany.
Wilfried BudachDepartment of Radiation Oncology, Heinrich Heine University, Moorenstr. 5, 40225, Düsseldorf, Germany.
Stefanie CorradiniDepartment of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.
Ute GanswindtDepartment of Radiation Oncology, Innsbruck, Austria.
Dieter HäussingerClinic of Gastroenterology, Hepatology und Infectious Diseases, Heinrich Heine University, Düsseldorf, Germany.
Torsten FeldtClinic of Gastroenterology, Hepatology und Infectious Diseases, Heinrich Heine University, Düsseldorf, Germany.
Hubert SchelzigDepartment of Vascular Surgery, Heinrich Heine University, Düsseldorf, Germany.
Hans BojarNEXTGEN ONCOLOGY GROUP, Düsseldorf, Germany.
Matthias PeiperHeinrich-Heine-University, Düsseldorf, Germany.
Edwin BölkeDepartment of Radiation Oncology, Heinrich Heine University, Moorenstr. 5, 40225, Düsseldorf, Germany. boelke@med.uni-duesseldorf.de.
Jan HaussmannDepartment of Radiation Oncology, Heinrich Heine University, Moorenstr. 5, 40225, Düsseldorf, Germany.
Christiane MatuschekDepartment of Radiation Oncology, Heinrich Heine University, Moorenstr. 5, 40225, Düsseldorf, Germany.
Heinrich Heine University Düsseldorf · DEInnsbruck Medical University · ATLudwig-Maximilians-Universität München · DEMaastricht University · NLNanjing Tech University · CNUniversität Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid spread of the corona virus pandemic is an existential problem for many people in numerous countries. So far, there is no effective vaccine protection or proven therapy available against the SARS-CoV-2 virus. In this review, we describe the role of passive immunization in times of the corona virus. Passive immunization could be a bridging technology to improve the immune defense of critically ill patients until better approaches with effective medications are available.

Indexed as

Immunization, PassiveBetacoronavirusCoronavirus InfectionsCOVID-19HumansPandemicsPneumonia, ViralSARS-CoV-2Bridge therapyConvalescent plasmaCovid-19High riskImmunologyIntensive care unitRespiratory failure

Identifiers

PMID32404189
PMCPMC7220618
OpenAlexW3025192328

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.