Evidence map›Paper›PMID 32404065›Full record

ArticleBMC neurology2020

Intrathecal blood injection: a case report of a rare complication of an epidural blood patch.

Joseph Seemiller, Sankeerth Challagundla, Travis Taylor, Ramin Zand

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Recent update on epidural blood patch.Anesthesia and pain medicine · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joseph SeemillerDepartment of Neurology, Neuroscience Institute, Geisinger Medical Center, 100 N. Academy Ave, Danville, PA, 17822, USA. joe@josephseemiller.com.ORCID http://orcid.org/0000-0001-7742-8759
Sankeerth ChallagundlaDepartment of Neurology, Neuroscience Institute, Geisinger Medical Center, 100 N. Academy Ave, Danville, PA, 17822, USA.
Travis TaylorDepartment of Neurology, Neuroscience Institute, Geisinger Medical Center, 100 N. Academy Ave, Danville, PA, 17822, USA.
Ramin ZandDepartment of Neurology, Neuroscience Institute, Geisinger Medical Center, 100 N. Academy Ave, Danville, PA, 17822, USA.
Geisinger Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntrathecal injection is a rare complication of spinal anesthesia and an underreported complication of epidural blood patches. Although there are other reported cases of intrathecal blood injection, these cases lack confirmatory imaging and others report injection of mixed blood with other agents. CASE PRESENTATION: We present a case report of post-laminectomy cerebrospinal fluid leak who underwent epidural blood patch placement. CT and MRI brain imaging was obtained, depicting intrathecal blood products. The patient had subsequent seizures and respiratory distress, received supportive care, and returned to baseline after several days.

conclusionThe patient's clinical course illustrates the potential complications of blood products within CSF, including seizures and respiratory distress, which improved with supportive care in this case. Importantly, to our knowledge, this is the only report that clearly depicts injection of purely blood products, without other confounding agents (such as gadolinium), into intrathecal space and with diffuse spread through the CSF as visualized on CT and MRI imaging.

Indexed as

Blood Patch, EpiduralCerebrospinal Fluid LeakHumansLaminectomyMaleMiddle AgedRespiratory Distress SyndromeSeizuresEpidural blood patchIntrathecal injectionLow pressure headacheProcedural complications

Identifiers

PMID32404065
PMCPMC7222553
OpenAlexW3024448248

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.