Evidence map›Paper›PMID 32404056›Full record

Trial reportBMC gastroenterology2020

Effectiveness of concomitant use of green tea and polyethylene glycol in bowel preparation for colonoscopy: a randomized controlled study.

Zong Hao, Lifeng Gong, Qiang Shen, Huipeng Wang, Shaowen Feng, Xin Wang, Yuankun Cai, Jun Chen

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. An abdominal vibration combined with walking exercise (AVCWE) program for older patients with constipation: Development and feasibility study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2024
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zong HaoDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China.
Lifeng GongDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China.
Qiang ShenDepartment of Endoscopic Center, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China.
Huipeng WangDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China.
Shaowen FengDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China.
Xin WangDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China.
Yuankun CaiDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China. 18918168583@163.com.
Jun ChenDepartment of Colorectal Surgery, Peking University International Hospital, Beijing, 102206, China. chenjun@pkuih.edu.cn.
Fudan University · CNPeking University · CN

Funding

Shanghai Minhang Science and Technology Commission 2015MHZ004Shanghai Minhang Science and Technology Commission 2015MHZ071
6 · The paper itself

Abstract

backgroundPolyethylene glycol solution (PEG) is widely used for bowel preparation prior to colonoscopies. However, patients often exhibited adverse events as nausea, vomit and distention due to its uncomfortable tastes and potential side affects. This study aimed to evaluate the effectiveness and safety of concomitant use of green tea (GT) with PEG in bowel preparation prior to colonoscopy.

methodsThis was a prospective, randomized controlled study. It was conducted at an outpatient setting of colorectal surgery in a tertiary hospital. Patients aged 18 through 80 who were scheduled to undergo colonoscopy between August 2015 and February 2016 were randomly assigned into two groups, admitting either 2 L-PEG solutions with 1 L GT liquids or 2 L-PEG solutions only for bowel preparation. Admitted doses of PEG solutions, taste evaluation, adverse reactions (nausea and vomiting, distention and abdominal pain) were investigated by questionnaires. The bowel cleanliness of each patient was evaluated according to the Aronchick indicators.

resultsA total of 116 patients were enrolled in this study (PEG+GT 59, PEG 57). Full compliances were achieved in 93.2% patients of group PEG+GT and 59.6% of group PEG (p < 0.001). Mean Aronchick scale between two groups were 2.0 ± 0.9 versus 2.2 ± 0.7 respectively (PEG+GT vs PEG, p = 0.296). Rates of adverse events as nausea and vomiting, abdominal pain in bowel preparation were significantly different between two groups (55.9% vs 77.2%, p = 0.015 and 13.6% vs 33.3%, p = 0.012). Patients in group PEG+GT who have probabilities to receive repeating colonoscopy had a higher willingness to accept PEG+GT again for bowel preparation, compared with PEG group (94.9% vs 57.9%, p < 0.001).

conclusionsConcomitant use of green tea and polyethylene glycol may effectively reduce incidence of adverse events, increase compliances, with comparable bowel cleanliness in bowel preparation.

trial registrationThis trial was retrospectively registered on Feb 1st, 2019 (ChiCTR1900021178).

Indexed as

ColonoscopyTeaAbdominal PainAdultAgedCatharticsCombined Modality TherapyFemaleHumansMaleMiddle AgedNauseaPatient CompliancePatient SatisfactionPolyethylene GlycolsPreoperative CareCatharticsPolyethylene GlycolsTeaAdverse reactionBowel preparationColonoscopyGreen teaPolyethylene glycol

Identifiers

PMID32404056
PMCPMC7218831
OpenAlexW3026147760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.