Evidence map›Paper›PMID 32404046›Full record

ArticleThe journal of headache and pain2020

Pain rates in general population for the period 1991-2015 and 10-years prediction: results from a multi-continent age-period-cohort analysis.

Davide Guido, Matilde Leonardi, Blanca Mellor-Marsá, Maria V Moneta, Albert Sanchez-Niubo, Stefanos Tyrovolas, Iago Giné-Vázquez, Josep M Haro, Somnath Chatterji, Martin Bobak and 8 more

Abstract read
In one paragraph

Article in The journal of headache and pain, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Association between quality of life before an acute pain event and the development of chronic pain-related disability.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Davide GuidoNeurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.
Matilde LeonardiNeurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy. matilde.leonardi@istituto-besta.it.
Blanca Mellor-MarsáParc Sanitari Sant Joan de Déu, Fundacion Sant Joan de Deu, Barcelona, Spain.
Maria V MonetaParc Sanitari Sant Joan de Déu, Fundacion Sant Joan de Deu, Barcelona, Spain.
Albert Sanchez-NiuboParc Sanitari Sant Joan de Déu, Fundacion Sant Joan de Deu, Barcelona, Spain.
Stefanos TyrovolasParc Sanitari Sant Joan de Déu, Fundacion Sant Joan de Deu, Barcelona, Spain.
Iago Giné-VázquezParc Sanitari Sant Joan de Déu, Fundacion Sant Joan de Deu, Barcelona, Spain.
Josep M HaroParc Sanitari Sant Joan de Déu, Fundacion Sant Joan de Deu, Barcelona, Spain.
Somnath ChatterjiInformation, Evidence and Research, World Health Organization, Geneva, Switzerland.
Martin BobakResearch Department of Epidemiology and Public Health, University College London, London, UK.
Jose L Ayuso-MateosInstituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain.
Holger ArndtSPRING TECHNO GMBH & Co. KG, Bremen, Germany.
Ilona KoupilDepartment of Public Health Sciences, Centre for Health Equity Studies, Stockholm University, Stockholm, Sweden.
Jerome BickenbachDepartment of Health Sciences and Health Policy, University of Lucerne, Lucerne, Switzerland.
Seppo KoskinenFinnish Institute for Health and Welfare (THL), Helsinki, Finland.
Beata Tobiasz-AdamczykDepartment of Epidemiology and Population Studies, Faculty of Health Sciences, Jagiellonian University Medical College, Krakow, Poland.
Demosthenes PanagiotakosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Alberto RaggiNeurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
The Mexican Health and Aging Study - IIR01AG018016 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Rebeca Wong · 1999 to 2026
$22.6M
Towards improving the measurement of health and disability trends, the compressioR01AG034479 · NIA · WORLD HEALTH ORGANIZATION · PI CHATTERJI, SOMNATH · 2010 to 2014
$5.3M
Health disparities and agingin societies in transitionR01AG023522 · NIA · UNIVERSITY COLLEGE LONDON · PI MARMOT, MICHAEL G · 2004 to 2008
$2.2M
COLLABORATIVE STUDY OF AGING IN THE US AND AUSTRALIAR01AG008523 · NIA · DUKE UNIVERSITY · PI MYERS, GEORGE C · 1991 to 1995
–
Horizon 2020 Framework Programme 635316Medical Research Council MR/K021907/1NIA NIH HHS HHSN271201300071CNIA NIH HHS R01 AG008523NIA NIH HHS R01 AG018016NIA NIH HHS R01 AG023522NIA NIH HHS R01 AG034479NIA NIH HHS U01 AG009740Wellcome Trust
6 · The paper itself

Abstract

backgroundPain is a common symptom, often associated with neurological and musculoskeletal conditions, and experienced especially by females and by older people. The aims of this study are to evaluate the temporal variations of pain rates among general populations for the period 1991-2015 and to project 10-year pain rates.

methodsWe used the harmonized dataset of ATHLOS project, which included 660,028 valid observations in the period 1990-2015 and we applied Bayesian age-period-cohort modeling to perform projections up to 2025. The harmonized Pain variable covers the content "self-reported pain experienced at the time of the interview", with a dichotomous (yes or no) modality.

resultsPain rates were higher among females, older subjects, in recent periods, and among observations referred to cohorts of subjects born between the 20s and the 60s. The 10-year projections indicate a noteworthy increase in pain rates in both genders and particularly among subjects aged 66 or over, for whom a 10-20% increase in pain rate is foreseen; among females only, a 10-15% increase in pain rates is foreseen for those aged 36-50.

conclusionsProjected increase in pain rates will require specific interventions by health and welfare systems, as pain is responsible for limited quality of subjective well-being, reduced employment rates and hampered work performance. Worksite and lifestyle interventions will therefore be needed to limit the impact of projected higher pain rates.

Indexed as

AdultAgedAged, 80 and overBayes TheoremFemaleHumansIncidenceMaleMiddle AgedPainSelf ReportBayesian age period cohort modelEmploymentHeadache disordersMusculoskeletal disordersPainProjection

Identifiers

PMID32404046
PMCPMC7218619

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.