Evidence map›Paper›PMID 32403971›Full record

ArticleGut microbes2020

β-arrestin 2 quenches TLR signaling to facilitate the immune evasion of EPEC.

Zijuan Chen, Ruixue Zhou, Yihua Zhang, Doudou Hao, Yu Wang, Shichao Huang, Ningning Liu, Chunmei Xia, Nissan Yissachar, Feng Huang and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Zijuan ChenDepartment of Immunology, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University , Shanghai, China.
Ruixue ZhouDepartment of Immunology, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University , Shanghai, China.
Yihua ZhangDepartment of Immunology, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University , Shanghai, China.
Doudou HaoDepartment of Immunology, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University , Shanghai, China.
Yu WangDepartment of Microbiology and Biochemical Pharmacy, National Engineering Research Centre of Immunological Products, College of Pharmacy, Third Military Medical University , Chongqing, China.
Shichao HuangShanghai Key Laboratory of Signaling and Disease Research, Laboratory of Receptor-based Bio-medicine, the Collaborative Innovation Center for Brain Science, School of Life Sciences and Technology, Tongji University , Shanghai, China.
Ningning LiuSchool of Public Health, Shanghai Jiao Tong University School of Medicine , Shanghai, China.
Chunmei XiaDepartment of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University , Shanghai, China.ORCID 0000-0001-9845-9685
Nissan YissacharThe Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan Institute of Nanotechnology and Advanced Materials, Bar-Ilan University , Ramat-Gan, Israel.
Feng HuangBeijing Hospital of Traditional Chinese Medicine, Capital Medical University , Beijing, China.
Yiwei ChuDepartment of Immunology, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University , Shanghai, China.
Dapeng YanDepartment of Immunology, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University , Shanghai, China.
Shanghai Public Health Clinical Center · CNArmy Medical University · CNBar-Ilan University · ILCapital Medical University · CNFudan University · CNShanghai Jiao Tong University · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The protein translocated intimin receptor (Tir) from enteropathogenic

Indexed as

Immune EvasionAmino Acid MotifsAnimalsbeta-Arrestin 2Cells, CulturedCytokinesEnteropathogenic Escherichia coliEscherichia coli ProteinsHEK293 CellsHeLa CellsHumansMacrophagesMacrophages, PeritonealMAP Kinase Kinase Kinase 7MAP Kinase Kinase KinasesMiceArrb2 protein, mousebeta-Arrestin 2CytokinesEscherichia coli ProteinsMAP Kinase Kinase Kinase 7MAP Kinase Kinase KinasesProtein Tyrosine Phosphatase, Non-Receptor Type 6Ptpn6 protein, mouseReceptors, Cell SurfaceRNA, Small InterferingTir protein, E coliTNF Receptor-Associated Factor 6Toll-Like ReceptorsEPECimmune evasionTAK1TLR signalingTRAF6β-arrestin 2

Identifiers

PMID32403971
PMCPMC7524320
OpenAlexW3025329371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.