Evidence map›Paper›PMID 32403966›Full record

ArticleAdipocyte2020

Long term hypoxia during gestation alters perirenal adipose tissue gene expression in the lamb.

Dean A Myers, Krista Singleton, Kim Hyatt, Kanchan M Kaushal, Charles A Ducsay

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Adipocyte, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Dean A MyersDepartment of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Krista SingletonDepartment of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Kim HyattDepartment of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Kanchan M KaushalLawrence D. Longo M.D. Center for Perinatal Biology, School of Medicine, Loma Linda University, Loma Linda, CA, USA.
Charles A DucsayLawrence D. Longo M.D. Center for Perinatal Biology, School of Medicine, Loma Linda University, Loma Linda, CA, USA.
University of Oklahoma Health Sciences Center · USLoma Linda University · US

Funding

Uterine vascular responses to pregnancy and long term hypoxemiaP01HD031226 · NICHD · LOMA LINDA UNIVERSITY · PI ZHANG, LUBO · 1995 to 2014
$21.4M
Uterine Vascular Adaptation to Pregnancy and Chronic HypoxiaP01HD083132 · NICHD · LOMA LINDA UNIVERSITY · PI DUCSAY, CHARLES A · 2016 to 2020
$6.3M
NICHD NIH HHS P01 HD031226NICHD NIH HHS P01 HD083132
6 · The paper itself

Abstract

We previously reported that following long-term hypoxia (LTH), the ovine foetus exhibits enhanced expression of brown/beige adipose genes. This study was designed to determine if these changes are preserved after birth. Pregnant ewes were divided among three groups, 1) Control, sea level, 2) LTH, high altitude (3,820 m, LTH-HA) from ~ day 40 of gestation through ~14 days post-delivery and 3) LTH from ⁓ day 40 through day 137 of gestation then returned to the laboratory where atory reduced maternal PO

Indexed as

Gene Expression RegulationAdipose TissueAdipose Tissue, BrownAnimalsBiomarkersFemaleFetusGene Expression ProfilingHypoxiaPregnancySheepTranscriptomeUncoupling Protein 1BiomarkersUncoupling Protein 1adiposefoetushypoxiasheepUCP-1

Identifiers

PMID32403966
PMCPMC7238872
OpenAlexW3025084802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.