Evidence map›Paper›PMID 32403890›Full record

ReviewZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2020

[Research progress of liver sinusoidal endothelial cells in the regulation of liver microenvironment to affect liver fibrosis].

X X Deng, H Li, Z F Zhang, Q L Gu

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Frontiers in molecular biosciences · 2022
    Article
  3. [Pathogenic role of NDUFA13 inactivation in spontaneous hepatitis in mice and the mechanism].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

X X DengCentral Laboratory of the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China; Clinical College of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.
H LiCentral Laboratory of the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.
Z F ZhangCentral Laboratory of the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China; Clinical College of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.
Q L GuCentral Laboratory of the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China; Clinical College of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.
Chengdu University of Traditional Chinese Medicine · CN

Funding

Sichuan Science and Technology Program 2018SZ0401, 2017FZ0052
6 · The paper itself

Abstract

Liver sinusoidal endothelial cells (LSECs) are not only important intermediary cells for substance exchange between blood and hepatocytes, but also important hepatic non-parenchymal cells to cause liver fibrosis and cirrhosis because of chronic liver injury factors. It mainly regulates the liver microcirculation and participates in the development of hepatic fibrosis by interacting with hepatic stellate cells (HSCs), hepatocytes, Kupffer cells and mediating hepatic stiffness and hepatic angiogenesis. Hence, clarifying these mechanisms will help to explore new targets and strategies for the treatment of liver fibrosis.

Indexed as

Endothelial CellsHepatic Stellate CellsHepatocytesHumansKupffer CellsLiverLiver CirrhosisHepatic microenvironmentLiver fibrosisLiver sinusoidal endothelial cells

Identifiers

PMID32403890
PMCPMC12770294
OpenAlexW3026765327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.