Evidence map›Paper›PMID 32403488›Full record

ArticleOptics express2020

Background-suppressed SRS fingerprint imaging with a fully integrated system using a single optical parametric oscillator.

Alberto Lombardini, Pascal Berto, Julien Duboisset, Esben Ravn Andresen, Sandro Heuke, Edlef Büttner, Ingo Rimke, Sébastien Vergnole, Vasyl Shinkar, Philippe de Bettignies and 1 more

Abstract read
In one paragraph

Article in Optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. SRS-FISH: A high-throughput platform linking microbiome metabolism to identity at the single-cell level.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alberto Lombardini
Pascal Berto
Julien Duboisset
Esben Ravn Andresen
Sandro Heuke
Edlef Büttner
Ingo Rimke
Sébastien Vergnole
Vasyl Shinkar
Philippe de Bettignies
Hervé Rigneault

Funding

Deep-tissue super-resolved microscopy with multiphoton spatial frequency-modulated imaging (MP-SPIFI)R21MH117786 · NIMH · COLORADO STATE UNIVERSITY · PI BARTELS, RANDY A. · 2018 to 2019
$362k
Unrestricted super-resolution imaging deep in tissues through scattering immune spatial frequency modulated imagingR21EB025389 · NIBIB · COLORADO STATE UNIVERSITY · PI BARTELS, RANDY A. · 2018 to 2019
$362k
NIBIB NIH HHS R21 EB025389NIMH NIH HHS R21 MH117786
6 · The paper itself

Abstract

Stimulated Raman Scattering (SRS) imaging can be hampered by non-resonant parasitic signals that lead to imaging artifacts and eventually overwhelm the Raman signal of interest. Stimulated Raman gain opposite loss detection (SRGOLD) is a three-beam excitation scheme capable of suppressing this nonlinear background while enhancing the resonant Raman signal. We present here a compact electro-optical system for SRGOLD excitation which conveniently exploits the idler beam generated by an optical parametric oscillator (OPO). We demonstrate its successful application for background suppressed SRS imaging in the fingerprint region. This system constitutes a simple and valuable add-on for standard coherent Raman laser sources since it enables flexible excitation and background suppression in SRS imaging.

Identifiers

PMID32403488
PMCPMC7340376

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.