ArticleMolecules (Basel, Switzerland)2020
Plasmon-Enhanced Controlled Drug Release from Ag-PMA Capsules.
Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Recent Advances in the Application of Silver Nanoparticles for Enhancing Phototherapy Outcomes.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Exploration of inorganic nanoparticles for revolutionary drug delivery applications: a critical review.Discover nano · 2023Review
- Nano-Hybrid Au@LCCs Systems Displaying Anti-Inflammatory Activity.Materials (Basel, Switzerland) · 2022Article
- ICP-MS Determination of Antimicrobial Metals in Microcapsules.Molecules (Basel, Switzerland) · 2022Article
- State of the Art on Green Route Synthesis of Gold/Silver Bimetallic Nanoparticles.Molecules (Basel, Switzerland) · 2022Review
- Acrylate and Methacrylate Polymers' Applications: Second Life with Inexpensive and Sustainable Recycling Approaches.Materials (Basel, Switzerland) · 2021Review
- Intermolecular Forces Driving Hexamethylenetetramine Co-Crystal Formation, a DFT and XRD Analysis.Molecules (Basel, Switzerland) · 2021Article
- Article
- Shedding Light on the Chemistry and the Properties of Münchnone Functionalized Graphene.Nanomaterials (Basel, Switzerland) · 2021Article
- Antimicrobial Effect and Cytotoxic Evaluation of Mg-Doped Hydroxyapatite Functionalized with Au-Nano Rods.Molecules (Basel, Switzerland) · 2021Article
- Nanoparticles Engineering by Pulsed Laser Ablation in Liquids: Concepts and Applications.Nanomaterials (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Silver (Ag)-grafted PMA (poly-methacrylic acid, sodium salt) nanocomposite loaded with sorafenib tosylate (SFT), an anticancer drug, showed good capability as a drug carrier allowing on-demand control of the dose, timing and duration of the drug release by laser irradiation stimuli. In this study, the preparation of Ag-PMA capsules loaded with SFT by using sacrificial silica microparticles as templates was reported. A high drug loading (DL%) of ∼13% and encapsulation efficiency (EE%) of about 76% were obtained. The photo-release profiles were regulated via the adjustment of light wavelength and power intensity. A significant improvement of SFT release (14% vs. 21%) by comparing SFT-Ag-PMA capsules with Ag-PMA colloids under the same experimental conditions was observed. Moreover, an increase of drug release by up to 35% was reached by tuning the laser irradiation wavelength near to Ag nanoparticles' surface plasmon resonance (SPR). These experimental results together with more economical use of the active component suggest the potentiality of SFT-Ag-PMA capsules as a smart drug delivery system.
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