ArticleNutrients2020
Chyme Reinfusion in Intestinal Failure Related to Temporary Double Enterostomies and Enteroatmospheric Fistulas.
Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Chyme Reinfusion in Patients with High-Output Enterocutaneous Fistulas and Enterostomies Undergoing Surgical Reconstruction: A Systematic Literature Review and Meta-Analysis.Digestive diseases and sciences · 2025Pooled it
- Clinical management of high-output stoma: a systematic literature review and meta-analysis.Techniques in coloproctology · 2023Pooled it
- Chyme Reinfusion Restores the Regulatory Bile Salt-FGF19 Axis in Patients With Intestinal Failure.Hepatology (Baltimore, Md.) · 2021Trial
- Continuous extracorporeal chyme reinfusion using the veraflo system in open abdomen with duodenostomy: a case report.BMC surgery · 2026Article
- Chyme reinfusion via percutaneous endoscopic colostomy in type 1 short bowel syndrome with a defunctionalized but intact colon: short-term nutritional outcomes and parenteral support weaning.Frontiers in nutrition · 2026Article
- Advances in Nutritional and Therapeutic Strategies for Type 2 Intestinal Failure: A Narrative Review.Nutrition reviews · 2025Review
- Clinical practice in the management of enteroatmospheric fistula and fistuloclysis: a case report.Revista da Escola de Enfermagem da U S P · 2025Article
- Chyme reinfusion practices in the neonatal population.Pediatric surgery international · 2024Article
- A review of chyme reinfusion: new tech solutions for age old problems.Journal of the Royal Society of New Zealand · 2024Review
- Multiple portions enteral nutrition and chyme reinfusion of a blunt bowel injury patient with hyperbilirubinemia undergoing open abdomen: A case report.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2023Article
- Challenges and Opportunities in the Oral Delivery of Recombinant Biologics.Pharmaceutics · 2023Review
- Surgical Treatment of Short Bowel Syndrome-The Past, the Present and the Future, a Descriptive Review of the Literature.Children (Basel, Switzerland) · 2022Review
- Management of Enterocutaneous Fistula: A Review.JNMA; journal of the Nepal Medical Association · 2022Review
- A comparison of chyme reinfusion therapy methods: Two case studies.Intestinal Failure (New York, N.Y.)Article
- Successful parenteral nutrition weaning using a chyme re-infusion device: Case reports.Intestinal Failure (New York, N.Y.)Article
- Long-term medical nutrition therapy improves the outcome of an abdominal tuberculosis patient with intestinal failure, severe malnutrition, and high-risk refeeding syndrome: A case report.Intestinal Failure (New York, N.Y.)Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Some temporary double enterostomies (DES) or entero-atmospheric fistulas (EAF) have high output and are responsible for Type 2 intestinal failure. Intravenous supplementations (IVS) for parenteral nutrition and hydration compensate for intestinal losses. Chyme reinfusion (CR) artificially restores continuity pending surgical closure. CR treats intestinal failure and is recommended by European Society for Clinical Nutrition and Metabolism (ESPEN) and American Society for Parenteral and Enteral Nutrition (ASPEN) when possible. The objective of this study was to show changes in nutritional status, intestinal function, liver tests, IVS needs during CR, and the feasibility of continuing it at home. A retrospective study of 306 admitted patients treated with CR from 2000 to 2018 was conducted. CR was permanent such that a peristaltic pump sucked the upstream chyme and reinfused it immediately in a tube inserted into the downstream intestine. Weight, plasma albumin, daily volumes of intestinal and fecal losses, intestinal nitrogen, and lipid absorption coefficients, plasma citrulline, liver tests, and calculated indices were compared before and during CR in patients who had both measurements. The patients included 185 males and 121 females and were 63 ± 15 years old. There were 37 (12%), 269 (88%) patients with EAF and DES, respectively. The proximal small bowel length from the duodeno-jejunal angle was 108 ± 67 cm (
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