Evidence map›Paper›PMID 32403393›Full record

Trial reportBiosensors2020

Fecal Volatile Organic Compound Profiles are Not Influenced by Gestational Age and Mode of Delivery: A Longitudinal Multicenter Cohort Study.

Nancy Deianova, Sofia El Manouni El Hassani, Hendrik J Niemarkt, Veerle Cossey, Anton H van Kaam, Floor Jenken, Mirjam M van Weissenbruch, Esmee M Doedes, Kyra Baelde, Renee Menezes and 4 more

Open access · goldAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Biosensors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Nancy DeianovaDepartment of Pediatric Gastroenterology, Amsterdam UMC, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands.
Sofia El Manouni El HassaniDepartment of Pediatric Gastroenterology, Amsterdam UMC, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands.
Hendrik J NiemarktNeonatal Intensive Care Unit, Máxima Medical Center, 5504 DB Veldhoven, The Netherlands.
Veerle CosseyNeonatal Intensive Care Unit, University Hospitals Leuven, 3000 Leuven, Belgium.
Anton H van KaamNeonatal Intensive Care Unit, Amsterdam UMC, VU University Medical Center, 1081 HV Amsterdam, The Netherlands.
Floor JenkenNeonatal Intensive Care Unit, Wilhelmina Children's Hospital/University Medical Center Utrecht, 3508 AB Utrecht, The Netherlands.
Mirjam M van WeissenbruchNeonatal Intensive Care Unit, Amsterdam UMC, VU University Medical Center, 1081 HV Amsterdam, The Netherlands.
Esmee M DoedesDepartment of Pediatric Gastroenterology, Amsterdam UMC, VU University Medical Center, 1081 HV Amsterdam, The Netherlands.
Kyra BaeldeDepartment of Pediatric Gastroenterology, Amsterdam UMC, VU University Medical Center, 1081 HV Amsterdam, The Netherlands.
Renee MenezesBiostatistics Unit, Netherlands Cancer Institute (NKI), 1066 CX Amsterdam, The Netherlands.
Marc A BenningaDepartment of Pediatric Gastroenterology, Amsterdam UMC, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands.
Wouter J de JongeAmsterdam University Medical Centers, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology & Metabolism, 1105 BK Amsterdam, The Netherlands.
Nanne K de BoerDepartment of Gastroenterology and Hepatology, Amsterdam Gastroenterology and Metabolism Research Institute, Amsterdam UMC, VU University Medical Center, 1081 HV Amsterdam, The Netherlands.
Tim G de MeijDepartment of Pediatric Gastroenterology, Amsterdam UMC, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands.
Amsterdam UMC Location University of Amsterdam · NLAmsterdam UMC Location Vrije Universiteit Amsterdam · NLAmsterdam University Medical Centers · NLKU Leuven · BERadboud University Nijmegen · NLThe Netherlands Cancer Institute · NLUniversity Medical Center Utrecht · NL

Funding

Stichting Zeldzame Ziekten Fonds NA
6 · The paper itself

Abstract

Fecal volatile organic compounds (VOC) reflect human and gut microbiota metabolic pathways and their interaction. VOC behold potential as non-invasive preclinical diagnostic biomarkers in various diseases, e.g., necrotizing enterocolitis and late onset sepsis. There is a need for standardization and assessment of the influence of clinical and environmental factors on the VOC outcome before this technique can be applied in clinical practice. The aim of this study was to investigate the influence of gestational age (GA) and mode of delivery on the fecal VOC pattern in preterm infants born below 30 weeks of gestation. Longitudinal fecal samples, collected on days 7, 14, and 21 postnatally, were analyzed by an electronic nose device (Cyranose 320

Indexed as

Delivery, ObstetricGestational AgeCesarean SectionCohort StudiesFecesHumansInfant, NewbornIntensive Care Units, NeonatalProspective StudiesVolatile Organic CompoundsVolatile Organic Compoundselectronic noseeNoseflatographygestational agemetabolomicsmode of deliverypreterm infantsVOCvolatile organic compound

Identifiers

PMID32403393
PMCPMC7277672
OpenAlexW3023823951

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.