ArticleAntibiotics (Basel, Switzerland)2020
Antimicrobial Efficacy of Five Probiotic Strains Against Helicobacter pylori.
Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 38 citations in OpenAlex.
- From Laboratory to Real Clinical Practice: A Multidisciplinary Approach Towards the Next Probiotics.Antibiotics (Basel, Switzerland) · 2026Article
- Beyond Antibiotics: Alternative Strategies TargetingExpert reviews in molecular medicine · 2026Review
- Multimodal anti-Helicobacter pylori effects of Lactobacillus casei HY001: Evidence from in vitro and in vivo studies.PloS one · 2026Article
- Garvicin Q-producing Lactococcus garvieae LG3092: its role in mitigating dysbiosis and H. pylori-associated gastritis.NPJ biofilms and microbiomes · 2025Article
- Beyond antibiotics: probiotics as a promising ally againstFrontiers in pharmacology · 2025Review
- The Influence of Gastric Microbiota and Probiotics inBiomedicines · 2024Review
- Opportunities forMicroorganisms · 2024Review
- Anti-inflammatory effects of extracellular vesicles and cell-free supernatant derived from Lactobacillus crispatus strain RIGLD-1 on Helicobacter pylori-induced inflammatory response in gastric epithelial cells in vitro.Folia microbiologica · 2024Article
- Screening Probiotics for Anti-Foods (Basel, Switzerland) · 2024Article
- The Potential of Alternative Therapies and Vaccine Candidates againstPharmaceuticals (Basel, Switzerland) · 2023Review
- About Functional Foods: The Probiotics and Prebiotics State of Art.Antibiotics (Basel, Switzerland) · 2023Review
- IgYs: on her majesty's secret service.Frontiers in immunology · 2023Review
- The impacts of probiotics in eradication therapy of Helicobacter pylori.Archives of microbiology · 2022Review
- Antibacterial Effects of Bacteriocin PLNC8 againstFoods (Basel, Switzerland) · 2022Article
- Microbiota changes with fermented kimchi contributed to either the amelioration or rejuvenation ofJournal of clinical biochemistry and nutrition · 2021Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Treatment of Helicobacter pylori (H. pylori) infection is a challenge for clinicians. The large increase in drug-resistant strains makes the formulation of new therapeutic strategies fundamental. The frequent onset of side effects during antibiotic treatment (mainly due to intestinal dysbiosis) should not be underestimated as it may cause the interruption of treatment, failure of H. pylori eradication and clonal selection of resistant bacteria. Probiotic integration during antibiotic treatment can exert a dual function: a direct antagonistic effect on H. pylori and a balancing effect on dysbiosis. Therefore, it fulfills the definition of a new therapeutic strategy to successfully treat H. pylori infection. Data reported in literature give promising but discrepant results.
aimTo assess in vitro bacteriostatic and bactericidal activity of probiotic strains against H. pylori. MATERIALS AND
methodsL. casei, L. paracasei, L. acidophilus, B. lactis and S. thermophilus strains were used. Agar well diffusion and time-kill curves were carried out to detect bacteriostatic and bactericidal activity, respectively.
resultsAll probiotic strains showed both bacteriostatic and bactericidal activity vs. H. pylori.
conclusionsSuch findings prompted us to plan a protocol of treatment in which probiotics are given to infected patients in association with antibiotic therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.