Evidence map›Paper›PMID 32403239›Full record

ArticleLife (Basel, Switzerland)2020

High-Throughput Identification of MiR-145 Targets in Human Articular Chondrocytes.

Aida Martinez-Sanchez, Stefano Lazzarano, Eshita Sharma, Helen Lockstone, Christopher L Murphy

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Exercise AltersMicroRNA (Shariqah, United Arab Emirates) · 2024
    Article
  5. Article
  6. Aging and obesity prime the methylome and transcriptome of adipose stem cells for disease and dysfunction.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  7. Article
  8. Review
  9. microRNA-130b downregulation potentiates chondrogenic differentiation of bone marrow mesenchymal stem cells by targeting SOX9.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Aida Martinez-SanchezKennedy Institute of Rheumatology, University of Oxford, Oxford OX3 7FY, UK.ORCID 0000-0001-5142-2527
Stefano LazzaranoKennedy Institute of Rheumatology, University of Oxford, Oxford OX3 7FY, UK.
Eshita SharmaWellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
Helen LockstoneWellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
Christopher L MurphyKennedy Institute of Rheumatology, University of Oxford, Oxford OX3 7FY, UK.
University of Oxford · GBCentre for Human Genetics · GB

Funding

Medical Research Council G0900747 91070Wellcome TrustWellcome Trust 090532/Z/09/Z
6 · The paper itself

Abstract

MicroRNAs (miRNAs) play key roles in cartilage development and homeostasis and are dysregulated in osteoarthritis. MiR-145 modulation induces profound changes in the human articular chondrocyte (HAC) phenotype, partially through direct repression of

Indexed as

cartilagechondrocytemiRNAsRNA-immunoprecipitation

Identifiers

PMID32403239
PMCPMC7281014
OpenAlexW3022414933

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.