Evidence map›Paper›PMID 32403174›Full record

SynthesisJournal of the European Academy of Dermatology and Venereology : JEADV2021

Frailty screening in dermato-oncology practice: a modified Delphi study and a systematic review of the literature.

M E C van Winden, S Garcovich, K Peris, G Colloca, E M G J de Jong, M E Hamaker, P C M van de Kerkhof, S F K Lubeek

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Journal of the European Academy of Dermatology and Venereology : JEADV, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Exploration of the causality of frailty index on psoriasis: A Mendelian randomization study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  4. Article
  5. Identifying and prioritizing sustainability indicators for China's assessing demolition waste management using modified Delphi-analytic hierarchy process method.Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA · 2023
    Article
  6. Article
  7. Article
  8. A prospective, multicentre study to assess frailty in elderly patients with leg ulcers (GERAS study).Journal of the European Academy of Dermatology and Venereology : JEADV · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

M E C van WindenDepartment of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0001-5641-3371
S GarcovichInstitute of Dermatology, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID https://orcid.org/0000-0001-8967-6688
K PerisInstitute of Dermatology, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID https://orcid.org/0000-0002-5237-0463
G CollocaDepartment of Radiation Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID https://orcid.org/0000-0001-6763-0793
E M G J de JongDepartment of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0003-3872-5704
M E HamakerDepartment of Geriatrics, Diakonessenhuis, Zeist, The Netherlands.ORCID https://orcid.org/0000-0002-2261-9301
P C M van de KerkhofDepartment of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0003-0084-3131
S F K LubeekDepartment of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0003-2694-6059
Radboud University Nijmegen · NLUniversità Cattolica del Sacro Cuore · ITAgostino Gemelli University Polyclinic · ITDiakonessenhuis hospital · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAppropriate management and prevention of both under- and overtreatment in older skin cancer patients can be challenging. It could be helpful to incorporate frailty screening in dermato-oncology care, since frailty is associated with adverse health outcomes.

objectivesThis study aimed to identify and prioritize the requirements a frailty screening tool (FST) should fulfil in dermato-oncology practice and to select the best existing FST(s) for this purpose.

methodsA modified two-round Delphi procedure was performed among 50 Italian and Dutch specialists and patients to review and prioritize a list of potential FST requirements, using a 5-point Likert scale. Consensus was defined as a mean score of ≥4.0. A systematic literature search was performed to identify existing multidomain FSTs, which were then assessed on the requirements resulting from the modified Delphi procedure.

resultsConsensus was achieved on evaluation of comorbidities (4.3 ± 0.7), polypharmacy (4.0 ± 0.9) and cognition (4.1 ± 0.8). The FST should have appropriate measurement properties (4.0 ± 1.0), be quickly executed (4.2 ± 0.7), clinically relevant (4.3 ± 0.7), and both easily understandable (4.1 ± 1.2) and interpretable (4.3 ± 0.7). Of the 26 identified FSTs, four evaluated the content-related domains: the Geriatric-8 (G8), the modified Geriatric-8 (mG8), the Groningen Frailty Indicator (GFI) and the Senior Adult Oncology Program 2 (SAOP2) screening tool. Of these, the G8 was the most extensively studied FST, with the best psychometric properties and execution within 5 min.

conclusionsThe G8 appears the most suitable FST for assessing frailty in older adults with skin cancer, although clinical studies assessing its use in a dermato-oncology population are needed to further assess whether or not frailty in this particular patient group is associated with relevant outcomes (e.g. complications and mortality), as seen in previous studies in other medical fields.

Indexed as

FrailtyNeoplasmsAgedDelphi TechniqueFrail ElderlyGeriatric AssessmentHumansMedical Oncology

Identifiers

PMID32403174
PMCPMC7818261
OpenAlexW3025689049

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.