Evidence map›Paper›PMID 32401908›Full record

ArticleActa cirurgica brasileira2020

Poly (Lactic Acid) membrane and Sedum dendroideum extract favors the repair of burns in rats.

Juliane Peliçari Binotto, Larissa Giorgetti Mendes, Fernanda Oliveira de Gaspari Gaspi, Marcelo Augusto Marreto Esquisatto, Thiago Antonio Moretti de Andrade, Fernanda Aparecida Sampaio Mendonça, Gláucia Maria Tech Santos

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta cirurgica brasileira, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juliane Peliçari BinottoCentro Universitário, Fundação Hermínio Ometto, Araras, SP, Brazil.
Larissa Giorgetti MendesDepartment of Materials Engineering and Bioprocess, School of Chemical Engineering, Universidade Estadual de Campinas, Brazil.
Fernanda Oliveira de Gaspari GaspiCentro Universitário, FHO, Araras, SP, Brazil.
Marcelo Augusto Marreto EsquisattoGraduate Program in Biomedical Sciences, Centro Universitário, FHO, Araras, SP, Brazil.
Thiago Antonio Moretti de AndradeGraduate Program in Biomedical Sciences, Centro Universitário, FHO, Araras, SP, Brazil.
Fernanda Aparecida Sampaio MendonçaGraduate Program in Biomedical Sciences, Centro Universitário, FHO, Araras, SP, Brazil.
Gláucia Maria Tech SantosCentro Universitário, FHO, Araras, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the healing potential of the electrospinning membranes of Poly (Lactic Acid) (PLA) associated with Sedum dendroideum extract in burn injuries in rats.

methodsSeventy-five rats were submitted to burn injury on their back skin: (C) untreated; (F) with daily topical application of S. dendroideum extract; (M) with electrospinning membranes of PLA; (MF10) with electrospinning membranes of PLA with 10% S. dendroideum extract; (MF25) with electrospinning membranes of PLA with 25% S. dendroideum extract. Tissue samples were taken after 2, 6 and 14 days of the burn injury and were subjected to histomorfometric analysis of quantification of fibroblasts, collagen fibers, blood vessels, and inflammatory infiltrate Results: The histomorphometric analysis showed an increase in the number of fibroblasts, collagen fibers and blood vessels in the burns treated with membranes of PLA, associated or not with the 10% and 25% extract. The extract of S. dendroideum promoted the increase of collagen fibers.

conclusionThe electrospinning PLA membrane, isolated or associated with the S. dendrodeum extract, favored the healing of burn injuries in this experimental model, with an increase of fibroblasts, collagen fibers, and blood vessels. S. dendroideum isolated only stimulated the collagenesis.

Indexed as

Membranes, ArtificialAnimalsBurnsCombined Modality TherapyDisease Models, AnimalMalePlant ExtractsPolyestersRatsRats, WistarSedumWound HealingMembranes, ArtificialPlant ExtractsPolyesterspoly(lactide)

Identifiers

PMID32401908
PMCPMC7217594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.