Evidence map›Paper›PMID 32401767›Full record

ArticlePloS one2020

Incidence and risk factors for hyperglycemia in pregnancy among nulliparous women: A Brazilian multicenter cohort study.

Bianca F Nicolosi, Renato T Souza, Jussara Mayrink, Francisco E Feitosa, Edilberto A Rocha Filho, Débora F Leite, Janete Vettorazzi, Maria H Sousa, Maria L Costa, Philip N Baker and 4 more

Abstract readMulticenter Study
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. AI-Driven Fetal Liver Echotexture Analysis: A New Frontier in Predicting Neonatal Insulin Imbalance.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Bianca F NicolosiDepartment of Obstetrics and Gynecology, Botucatu Medical School, Unesp, Botucatu, SP, Brazil.
Renato T SouzaDepartment of Obstetrics and Gynecology, University of Campinas (UNICAMP) School of Medical Sciences, Campinas, SP, Brazil.
Jussara MayrinkDepartment of Obstetrics and Gynecology, University of Campinas (UNICAMP) School of Medical Sciences, Campinas, SP, Brazil.
Francisco E FeitosaMEAC-Maternity School of the Federal University of Ceará, in Fortaleza, CE, Brazil.
Edilberto A Rocha FilhoDepartment of Maternal and Child Health, Maternity of Clinic Hospital, Federal University of Pernambuco, Recife, PE, Brazil.
Débora F LeiteDepartment of Obstetrics and Gynecology, University of Campinas (UNICAMP) School of Medical Sciences, Campinas, SP, Brazil.
Janete VettorazziDepartment of Obstetrics and Gynecology, Maternity of the Clinic Hospital, Federal University of RS, Porto Alegre, RS, Brazil.
Maria H SousaStatistics Unit, Jundiai School of Medicine, Jundiaí, SP, Brazil.
Maria L CostaDepartment of Obstetrics and Gynecology, University of Campinas (UNICAMP) School of Medical Sciences, Campinas, SP, Brazil.
Philip N BakerCollege of Life Sciences, University of Leicester, Leicester, United Kingdom.
Louise C KennyFaculty of Health and Life Sciences, Department of Women's and Children's Health, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.
Jose G CecattiDepartment of Obstetrics and Gynecology, University of Campinas (UNICAMP) School of Medical Sciences, Campinas, SP, Brazil.ORCID 0000-0003-1285-8445
Iracema M CalderonDepartment of Obstetrics and Gynecology, Botucatu Medical School, Unesp, Botucatu, SP, Brazil.ORCID 0000-0003-4761-4336
Preterm SAMBA Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the incidence and risk factors for hyperglycemia in pregnancy in a cohort of Brazilian nulliparous pregnant women. MATERIALS AND

methodsThis is a secondary analysis of a multicenter cohort study that enrolled 1,008 nulliparous pregnant women at 19-21 weeks. Exclusion criteria included chronic exposure to corticosteroids and previous diabetes. Bivariate and multivariate analyses by Poisson regression were used to identify associated factors.

resultsThe incidence of hyperglycemia in pregnancy was 14.9% (150/1,008), and 94.7% of these cases were gestational diabetes mellitus (142/150). Significant associated factors included a family history of diabetes mellitus, maternal overweight or obesity at enrollment, and previous maternal conditions (polycystic ovarian syndrome, thyroid dysfunctions and hypertensive disorders). A BMI ≥ 26.3Kg/m2 (RRadj 1.87 [1.66-2.10]) and a family history of diabetes mellitus (RRadj 1.71 [1.37-2.15]) at enrollment were independent risk factors for HIP.

conclusionsA family history of diabetes mellitus and overweight or obesity (until 19-21 weeks of gestation) may be used as selective markers for HIP in Brazilian nulliparous women. Given the scarcity of results in nulliparous women, our findings may contribute to determine the optimal diagnostic approach in populations of similar socioeconomic characteristics.

Indexed as

AdultBrazilDiabetes, GestationalFemaleHumansHyperglycemiaIncidenceOverweightPregnancyPregnancy ComplicationsRisk FactorsYoung Adult

Identifiers

PMID32401767
PMCPMC7219776

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.