Evidence map›Paper›PMID 32401765›Full record

ArticlePloS one2020

Isolation of a novel species in the genus Cupriavidus from a patient with sepsis using whole genome sequencing.

Oh Joo Kweon, Yong Kwan Lim, Hye Ryoun Kim, Tae-Hyoung Kim, Sung-Min Ha, Mi-Kyung Lee

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Clinical Management of SevereInfectious disease reports · 2026
    Article
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  5. Article
  6. Severe pneumonia due toFrontiers in medicine · 2025
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  7. Whole genome sequence ofFrontiers in microbiology · 2025
    Article
  8. Article
  9. Article
  10. Genomic Sequencing of ClinicalInfection and drug resistance · 2024
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Oh Joo KweonDepartment of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
Yong Kwan LimDepartment of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-4300-8964
Hye Ryoun KimDepartment of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
Tae-Hyoung KimDepartment of Urology, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
Sung-Min HaChunLab, Inc., Seoul, Republic of Korea.
Mi-Kyung LeeDepartment of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
Chung-Ang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whole genome sequencing (WGS) has become an accessible tool in clinical microbiology, and it allowed us to identify a novel Cupriavidus species. We isolated Gram-negative bacillus from the blood of an immunocompromised patient, and phenotypical and molecular identifications were performed. Phenotypic identification discrepancies were noted between the Vitek 2 (bioMérieux, Marcy-l'Étoile, France) and Vitek MS systems (bioMérieux). Using 16S rRNA gene sequencing, it was impossible to identify the pathogen to the species levels. WGS was performed using the Illumina MiSeq platform (Illumina, San Diego, CA), and genomic sequence database searching with a TrueBacTM ID-Genome system (ChunLab, Inc., Seoul, Republic of Korea) showed no strains with average nucleotide identity values higher than 95.0%, which is the cut-off for species-level identification. Phylogenetic analysis indicated that the bacteria was a new Cupriavidus species that formed a subcluster with Cupriavidus gilardii. WGS holds great promise for accurate molecular identification beyond 16S rRNA gene sequencing in clinical microbiology.

Indexed as

CupriavidusDNA, BacterialFemaleGram-Negative Bacterial InfectionsHigh-Throughput Nucleotide SequencingHumansPhylogenyRepublic of KoreaSepsisWhole Genome SequencingYoung AdultDNA, Bacterial

Identifiers

PMID32401765
PMCPMC7219751
OpenAlexW3024573430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.