Evidence map›Paper›PMID 32401669›Full record

ArticleThe neuroradiology journal2020

Diffuse large B-cell lymphoma relapse presenting as extensive neurolymphomatosis.

Pankaj Nepal, Prem P Batchala, Patrice K Rehm, Camilo E Fadul

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The neuroradiology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pankaj NepalDepartment of Radiology and Medical Imaging, St. Vincent's Medical Center, Bridgeport, CT, USA.
Prem P BatchalaDepartment of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, VA, USA.ORCID https://orcid.org/0000-0002-3744-7012
Patrice K RehmDepartment of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, VA, USA.
Camilo E FadulDivision of Neuro-oncology, Department of Neurology, University of Virginia Health System, Charlottesville, VA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 56-year-old woman with a history of diffuse large B-cell non-Hodgkin lymphoma (DLBCL-NHL) in remission for two years presented with weight loss and multifocal sensory/motor symptoms. Magnetic resonance imaging (MRI) of the neuraxis and whole-body FDG PET/CT led to a diagnosis of secondary neurolymphomatosis (NL). MRI demonstrated extensive thickening and enhancement of multiple cranial nerves and peripheral nerve plexuses with corresponding elevated metabolism on FDG PET/CT. Treatment with chemotherapy resulted in complete response on FDG PET/CT and subsequently she underwent autologous stem cell transplantation. NL is a rare manifestation of lymphoma affecting the peripheral nervous system. Nonspecific neuropathic symptoms make clinical diagnosis difficult. Though nerve biopsy is considered the gold standard, MRI and FDG PET/CT are accepted alternatives for making the diagnosis. We review imaging findings in NL, describe the differential diagnosis, and discuss the limitations of the imaging modalities.

Indexed as

FemaleHumansLymphoma, Large B-Cell, DiffuseMiddle AgedNeoplasm Recurrence, LocalNeurolymphomatosisPeripheral NerveslymphomaMRINeurolymphomatosisperipheral nervous systemPET/CT

Identifiers

PMID32401669
PMCPMC7286191

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.