Evidence map›Paper›PMID 32401658›Full record

ArticleHuman vaccines & immunotherapeutics2020

Comparison of pneumococcal conjugate vaccine (PCV-13) cellular immune responses after primary and booster doses of vaccine.

Timothy J Chapman, Michael E Pichichero, Ravinder Kaur

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07242092 (Effect of Methotrexate Discontinuation on Immunogenicity of 20-valent Pneumococcal Conjugate Vaccine), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07242092 phase4recruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Methotrexate Discontinuation on Immunogenicity of 20-valent Pneumococcal Conjugate Vaccine (PCV20) in Patients With Autoimmune Rheumatic Diseases

TypeinterventionalSponsorUniversity of Sao Paulo General HospitalRan2026 to 2028Enrolled192ConditionsAutoimmune Rheumatic DiseasesArmsPneumococcal Vaccine
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Timothy J ChapmanCenter for Infectious Diseases and Immunology, Rochester General Hospital Research Institute , Rochester, NY, USA.ORCID 0000-0002-2337-2136
Michael E PichicheroCenter for Infectious Diseases and Immunology, Rochester General Hospital Research Institute , Rochester, NY, USA.
Ravinder KaurCenter for Infectious Diseases and Immunology, Rochester General Hospital Research Institute , Rochester, NY, USA.
Rochester General Hospital · US

Funding

Antibody & Cellular Immune responses in children after 2 vs 3 doses and pre vs post booster of PCV13 VaccineR03HD088909 · NICHD · ROCHESTER GENERAL HOSPITAL (NY) · PI KAUR, RAVINDER · 2017 to 2018
$170k
NICHD NIH HHS R03 HD088909
6 · The paper itself

Abstract

Since their widespread use, pneumococcal conjugate vaccines (PCVs) have proven effective at reducing both invasive and noninvasive pneumococcal diseases and nasopharyngeal carriage of

Indexed as

Antibodies, BacterialPneumococcal InfectionsPneumococcal VaccinesChildChild, PreschoolHumansImmunity, CellularImmunization, SecondaryInfantVaccines, ConjugateAntibodies, BacterialPneumococcal VaccinesVaccines, ConjugateB-cell memorypneumococcal conjugate vaccine-13Streptococcus pneumoniaeT-cell memory

Identifiers

PMID32401658
PMCPMC8641578
OpenAlexW3025914624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.