Evidence map›Paper›PMID 32401588›Full record

ArticleCell cycle (Georgetown, Tex.)2020

Chrysophanol protects PC12 cells against oxygen glucose deprivation-evoked injury by up-regulating miR-216a.

Yuanyuan Liu, Chuanqian Liu, Xueting Zhang, Zhenzhen Liu, Xipeng Yan

RetractedOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yuanyuan LiuDepartment of Neurology, Jining No.1 People's Hospital , Jining, China.
Chuanqian LiuDepartment of Traditional Chinese Medicine, Jining No.1 People's Hospital , Jining, China.
Xueting ZhangDepartment of Traditional Chinese Medicine, Jining No.1 People's Hospital , Jining, China.
Zhenzhen LiuDepartment of Traditional Chinese Medicine, Jining No.1 People's Hospital , Jining, China.
Xipeng YanDepartment of Traditional Chinese Medicine, Jining No.1 People's Hospital , Jining, China.ORCID 0000-0002-1449-6014
Jining Traditional Chinese Medicine Hospital · CNJining First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCerebral stroke refers to an acute onset of neurological deficit syndrome. In this research, we attempted to probe into the underlying mechanisms by which chrysophanol (CP) performed its regulatory roles in cerebral stroke.

Indexed as

AnimalsAnthraquinonesApoptosisCell ProliferationGlucoseJanus Kinase 2MicroRNAsNeuroprotective AgentsOxygenPC12 CellsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktRatsSignal TransductionSTAT3 Transcription FactorUp-RegulationAnthraquinoneschrysophanic acidGlucoseJanus Kinase 2MicroRNAsMIRN216 microRNA, ratNeuroprotective AgentsOxygenPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSTAT3 Transcription Factorcerebral strokeChrysophanolmiR-216aoxygen and glucose deprivationPI3K/AKT and JAK2/STAT3 pathways

Identifiers

PMID32401588
PMCPMC7469580
OpenAlexW3024998653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.