Evidence map›Paper›PMID 32401196›Full record

ArticleeLife2020

Synergism of type 1 metabotropic and ionotropic glutamate receptors in cerebellar molecular layer interneurons in vivo.

Jin Bao, Michael Graupner, Guadalupe Astorga, Thibault Collin, Abdelali Jalil, Dwi Wahyu Indriati, Jonathan Bradley, Ryuichi Shigemoto, Isabel Llano

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Deconstruction of Vermal Cerebellum in Ramp Locomotion in Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Jin BaoUniversité de Paris, CNRS, SPPIN - Saints-Pères Paris Institute for the Neurosciences, Paris, France.ORCID 0000-0003-1234-5578
Michael GraupnerUniversité de Paris, CNRS, SPPIN - Saints-Pères Paris Institute for the Neurosciences, Paris, France.ORCID 0000-0002-1197-2388
Guadalupe AstorgaUniversité de Paris, CNRS, SPPIN - Saints-Pères Paris Institute for the Neurosciences, Paris, France.
Thibault CollinUniversité de Paris, CNRS, SPPIN - Saints-Pères Paris Institute for the Neurosciences, Paris, France.
Abdelali JalilUniversité de Paris, CNRS, SPPIN - Saints-Pères Paris Institute for the Neurosciences, Paris, France.
Dwi Wahyu IndriatiDivision of Cerebral Structure, National Institute for Physiological Sciences, The Graduate University for Advanced Studies (Sokendai), Okazaki, Japan.
Jonathan BradleyUniversité de Paris, CNRS, SPPIN - Saints-Pères Paris Institute for the Neurosciences, Paris, France.ORCID 0000-0002-6933-1153
Ryuichi ShigemotoDivision of Cerebral Structure, National Institute for Physiological Sciences, The Graduate University for Advanced Studies (Sokendai), Okazaki, Japan.ORCID 0000-0001-8761-9444
Isabel LlanoUniversité de Paris, CNRS, SPPIN - Saints-Pères Paris Institute for the Neurosciences, Paris, France.ORCID 0000-0002-7217-9711
Centre National de la Recherche Scientifique · FRInstitute of Science and Technology Austria · ATNational Institute for Physiological Sciences · JP

Funding

Agence Nationale de la Recherche ANR-11BSV401001Agence Nationale de la Recherche ANR-18-CE16-0010-01National Natural Science Foundation of China 31571073National Natural Science Foundation of China 81401025
6 · The paper itself

Abstract

Type 1 metabotropic glutamate receptors (mGluR1s) are key elements in neuronal signaling. While their function is well documented in slices, requirements for their activation in vivo are poorly understood. We examine this question in adult mice in vivo using 2-photon imaging of cerebellar molecular layer interneurons (MLIs) expressing GCaMP. In anesthetized mice, parallel fiber activation evokes beam-like Ca

Indexed as

Synaptic TransmissionAnimalsBiosensing TechniquesCalcium-Binding ProteinsCalcium SignalingCerebellumFemaleInterneuronsLuminescent ProteinsMiceMicroscopy, Fluorescence, MultiphotonMotor ActivityReceptors, Ionotropic GlutamateReceptors, Metabotropic GlutamateWalkingCalcium-Binding ProteinsLuminescent Proteinsmetabotropic glutamate receptor type 1Receptors, Ionotropic GlutamateReceptors, Metabotropic Glutamatecalcium imagingcerebellumglutamate receptorsin vivomglursmouseneuroscienceparallel fiber

Identifiers

PMID32401196
PMCPMC7220378
OpenAlexW3025567901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.