ArticleAllergy2020
APPEAL-1: A multiple-country European survey assessing the psychosocial impact of peanut allergy.
Article in Allergy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 57 citations in OpenAlex.
- Trial
- Understanding Family Burden Associated with Pediatric Food Allergy: Contributions of Child Neophobia and Maternal Personality Traits.Journal of clinical psychology in medical settings · 2026Article
- Understanding patient perceptions, knowledge, and experience of perioperative allergic reactions: a qualitative interview study.British journal of anaesthesia · 2025Article
- Food Allergy-Related Bullying in Pediatric Patients: A Systematic Review.Children (Basel, Switzerland) · 2024Review
- Key factors that influence quality of life in patients with IgE-mediated food allergy vary by age.Allergy · 2024Article
- Selecting patients for food allergy therapy.Journal of food allergy · 2024Article
- Evaluation and Modification of a Shared Decision-Making Tool for Peanut Allergy Management.Current allergy and asthma reports · 2024Review
- Awareness of Food Allergies and Allergens on the Menus of Restaurants and Cafes among Saudi Female University Students.Healthcare (Basel, Switzerland) · 2023Article
- Post hoc analysis examining symptom severity reduction and symptom absence during food challenges in individuals who underwent oral immunotherapy for peanut allergy: results from three trials.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023Article
- Living with food allergies: the experiences of adult patients and caregivers.Frontiers in allergy · 2023Article
- Mass cytometry analysis of blood from peanut-sensitized tolerant and clinically allergic infants.Scientific data · 2022Article
- Children and caregiver proxy quality of life from peanut oral immunotherapy trials.Clinical and translational allergy · 2022Article
- Children at risk of anaphylaxis: A mixed-studies systematic review of parents' experiences and information needs.PEC innovation · 2022Review
- Long Non-Coding RNAs Expressed in the Peanut Allergy for Understanding the Pathophysiology of Peanut Allergy Rat Model.Foods (Basel, Switzerland) · 2022Article
- Article
- Learning Early About Peanut worries: Evaluation of parental PROMIS-29 anxiety scores during early peanut introduction clinics.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022Article
- Exploring Health-Related Quality of Life Burden in Peanut Allergy and the Potential Benefit of Oral Immunotherapy: Estimation of Health State Utility Values for Children and Adolescents and Their Caregivers.Patient preference and adherence · 2022Article
- Article
- S3 guideline Allergy Prevention.Allergologie select · 2022Article
- Oral Immunotherapy in Food Allergy: A Critical Pediatric Perspective.Frontiers in pediatrics · 2022Review
Corrections and comments
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Authors and funding
16 authors at 8 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeanut allergy (PA) is a common, potentially life-threatening and typically lifelong condition with a significant burden of illness. However, information is lacking on how persons with PA (PwPA) and their caregivers perceive the psychosocial impact of living with PA. The Allergy to Peanuts imPacting Emotions And Life 1 (APPEAL-1) survey, conducted across Europe, investigated the experience and impact of living with PA. Here, we report data evaluating the psychosocial impact of PA on PwPA and their caregivers.
methodsAllergy to Peanuts imPacting Emotions And Life study 1 was an online survey conducted in eight European countries. Representatives of eight patient advocacy groups and five healthcare-research specialists developed the survey. Eligible respondent groups included the following: adults diagnosed with PA (self-report); parent/nonparent caregivers (proxy-report for a child with PA); and parent/nonparent caregivers (self-report of PA impact on themselves).
resultsOf 1846 total study respondents, 419 were adults with PA (self-report); 546 were parents/caregivers (proxy-report); and 881 were parents/caregivers (self-report). Most respondents reported lifestyle restrictions regarding food (84%-93%) and additional domains including parties and socializing, holiday activities and destinations, and taking public transport (53%-89%). Approximately 40% rated themselves as "very" frustrated and "very" stressed. Two-thirds (65%) felt socially isolated; 43% were bullied. Less than half felt confident in knowing when to use an adrenaline autoinjector. Several intercountry differences were observed such as high levels of uncertainty and stress in respondents from Ireland, highest rates of anxiety in respondents from Germany, and social exclusion and isolation most common in respondents from France.
conclusionsPeanut allergy imposes an adverse psychosocial impact on patients and caregivers, leading to frustration, stress and isolation. Attention to the impact of PA is needed in research and clinical practice to improve PA healthcare and public education programmes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.