Evidence map›Paper›PMID 32400209›Full record

ArticlePsychology & health2021

Syndemics and salivary inflammation in people living with HIV/AIDS.

Brooke G Rogers, Tiffany R Glynn, Sierra A Bainter, Thomas McCauley, Michael H Antoni, Steven A Safren

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychology & health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Brooke G RogersDepartment of Psychology, University of Miami, Coral Gables, FL, USA.ORCID 0000-0002-8569-9556
Tiffany R GlynnDepartment of Psychology, University of Miami, Coral Gables, FL, USA.
Sierra A BainterDepartment of Psychology, University of Miami, Coral Gables, FL, USA.ORCID 0000-0001-7461-0803
Thomas McCauleyDepartment of Psychology, University of Miami, Coral Gables, FL, USA.
Michael H AntoniDepartment of Psychology, University of Miami, Coral Gables, FL, USA.
Steven A SafrenDepartment of Psychology, University of Miami, Coral Gables, FL, USA.ORCID 0000-0002-0121-0806
University of Miami · US

Funding

The University of Miami AIDS Research Center on Mental Health and HIV/AIDS - Center for HIV & Research in Mental Health (CHARM)Research Core & MHD-CEP30MH133399 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI Audrey Harkness · 2023 to 2026
$8.9M
University of Miami Developmental HIV/AIDS Mental Health Research Center (D-ARC)P30MH116867 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2019 to 2023
$6.5M
Addressing psychosocial comorbidities in HIV treatment and preventionK24DA040489 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2016 to 2020
$931k
Bayesian Variable Selection Methods to Accelerate Identification of Important Psychological Predictors and Neural Substrates of PsychopathologyK01MH122805 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI BAINTER, SIERRA · 2020 to 2024
$659k
Mechanisms and Health Impact of Insomnia as an HIV ComorbidityF31MH113481 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI ROGERS, BROOKE GENKIN · 2017 to 2017
$44k
NIDA NIH HHS K24 DA040489NIMH NIH HHS F31 MH113481NIMH NIH HHS K01 MH122805NIMH NIH HHS P30 MH116867NIMH NIH HHS P30 MH133399
6 · The paper itself

Abstract

objectivePeople living with HIV/AIDS (PLWHA) are disproportionally exposed to a host of structural, community, and individual-level physical and psychosocial stressors also termed 'syndemic conditions.' The current study aimed to examine the association between experiencing syndemic conditions and physiological stress response and be associated with bodily inflammation, including Interlekin-6 (IL-6) and C-reactive protein (CRP) in PLWHA.

designParticipants (N = 103) were recruited from a public HIV clinic. They provided saliva samples of IL-6 and CRP and completed psychosocial measures.

main outcome measuresLevels of circulating salivary IL-6 and CRP.

resultsWhen predictors (birth country, recent housing instability, and incarceration history) were simultaneously entered into a regression model, only incarceration history was negatively associated with IL-6 [b = -.27,

conclusionAlthough we had expected higher levels of syndemics to be associated with higher levels of circulating inflammation, in our sample, length of incarceration was associated with lower levels of circulating IL-6. Findings are therefore suggestive of a stress response disruption resulting in a negative feedback loop as the long-term impact of chronic stress on inflammation.

Indexed as

HIV InfectionsInflammationSyndemicFemaleHumansMaleMiddle AgedSalivacytokinesHIVinflammationsyndemic

Identifiers

PMID32400209
PMCPMC7665986
OpenAlexW3024216498

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.