Evidence map›Paper›PMID 32400079›Full record

ArticleJournal of cardiovascular electrophysiology2020

Patient-reported outcomes after cryoballoon ablation are equivalent between moderate sedation and general anesthesia.

Jeremiah Wasserlauf, Rachel M Kaplan, David R Walega, Rishi Arora, Alexandru B Chicos, Susan S Kim, Albert C Lin, Nishant Verma, Kaustubha D Patil, Bradley P Knight and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Sedation vs. general anaesthesia in patients with atrial fibrillation undergoing catheter ablation: a systematic review and meta-analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Pooled it
  2. Trial
  3. Article
  4. Improved patient value after implementing same day discharge for patients undergoing pulmonary vein isolation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  5. Anaesthetic Techniques for Cardiac Ablation-A Scoping Review.Acta anaesthesiologica Scandinavica · 2026
    Article
  6. Article
  7. Feasibility of deep sedation for catheter ablation of atrial fibrillation using pulsed field ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
  8. Article
  9. Observational
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Jeremiah WasserlaufDivision of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0002-4497-3520
Rachel M KaplanDivision of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
David R WalegaDepartment of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Rishi AroraDivision of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0002-0725-4332
Alexandru B ChicosDivision of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Susan S KimDivision of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Albert C LinDivision of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Nishant VermaDivision of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0003-4817-6614
Kaustubha D PatilDivision of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0003-4592-1383
Bradley P KnightDivision of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0002-2129-0401
Rod S PassmanDivision of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Northwestern University · US

Funding

Pathophysiological Significance of Atrial Fibrillation Electrogram PatternsR01HL125881 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ARORA, RISHI · 2015 to 2019
$2.4M
Oxidative stress contributes to atrial fibrillation by causing remodeling of the autonomic nervous systemR01HL140061 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ARORA, RISHI · 2018 to 2021
$2.3M
NHLBI NIH HHS R01 HL125881NHLBI NIH HHS R01 HL140061
6 · The paper itself

Abstract

introductionModerate sedation (MS) during cryoballoon ablation (CBA) avoids risks of general anesthesia (GA) and improves electrophysiology (EP) lab throughput. However, one barrier to the use of MS is the potential for patient discomfort. The objective of this study was to compare patient-reported outcome measures following CBA for paroxysmal atrial fibrillation (pAF) under MS and GA. METHODS AND

resultsConsecutive patients undergoing a first CBA for pAF under GA or MS were prospectively enrolled. The sedation method was assigned based on patient and provider preference, and perceived airway risk. The primary outcomes were quality of recovery (measured using a validated 40 question survey; QoR-40) and likelihood to recommend (LTR) the procedure and sedation method (measured by Likert scale). Secondary outcomes were acute pulmonary vein (PV) isolation rate, procedure, fluoroscopy and ablation times, and complication rates. Forty-seven GA and 53 MS patients were included. The mean age was 64.9 ± 9.4 years and mean CHA

conclusionMS for CBA offers an alternative to GA that is safe and well-tolerated by patients with comparable success rates and improved EP lab throughput.

Indexed as

Anesthesia, GeneralAtrial FibrillationCatheter AblationCryosurgeryPatient Reported Outcome MeasuresPulmonary VeinsAgedHumansMiddle AgedProcedural SedationTreatment Outcomeanesthesiaatrial fibrillationcatheter ablationcryoballoon ablationpatient-reported outcomessatisfactionsedation

Identifiers

PMID32400079
PMCPMC9451135
OpenAlexW3025774742

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.