Evidence map›Paper›PMID 32399996›Full record

ArticleClinical transplantation2020

Long-term renal function in living kidney donors with simple renal cysts: A retrospective cohort study.

Madeleine M Waldram, Alvin G Thomas, Yifan Yu, Courtenay M Holscher, Anh Q Nguyen, Samantha E Halpern, Shane Ottman, Abimereki D Muzaale, Macey L Henderson, Krista L Lentine and 5 more

Open access · greenAbstract read
In one paragraph

Article in Clinical transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Madeleine M WaldramDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-5706-4353
Alvin G ThomasDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-4911-8192
Yifan YuDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Courtenay M HolscherDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-5808-5954
Anh Q NguyenDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Samantha E HalpernDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Shane OttmanDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Abimereki D MuzaaleDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-3287-6061
Macey L HendersonDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-4239-1252
Krista L LentineSaint Louis University Center for Abdominal Transplantation, St. Louis, Missouri, USA.
Fawaz Al AmmaryDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-0928-2860
Daniel C BrennanDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jacqueline M Garonzik-WangDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Dorry L SegevDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Allan B MassieDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Johns Hopkins University · USSaint Louis University · USUniversity of North Carolina at Chapel Hill · US

Funding

Cardiovascular Epidemiology Training GrantT32HL007055 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Wayne D. Rosamond · 1986 to 2026
$10.0M
Long-Term Health Outcomes After Live Kidney Donation in African AmericansR01DK096008 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2013 to 2017
$3.8M
Patient Oriented Research in Solid Organ TransplantationK24AI144954 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SEGEV, DORRY L. · 2020 to 2024
$956k
Patient Oriented Research in Kidney Disease and Transplant SurgeryK24DK101828 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2014 to 2018
$922k
Determinants of chronic kidney disease in African-American live kidney donorsK01DK101677 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI MASSIE, ALLAN B · 2015 to 2019
$789k
Technological Innovations for Live Kidney Donor Follow-up Care ManagementK01DK114388 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LEVAN, MACEY LEIGH · 2017 to 2021
$720k
Aggressive Center Report Cards to Safely Increase Transplantation of Suboptimal KidneysK23DK115908 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI GARONZIK WANG, JACQUELINE M · 2018 to 2021
$516k
Trajectory of post-donation renal function in living kidney donorsF32DK109662 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI HOLSCHER, COURTENAY · 2016 to 2018
$232k
NHLBI NIH HHS T32 HL007055NIAID NIH HHS K24 AI144954NIDDK NIH HHS F32 DK109662NIDDK NIH HHS K01 DK101677NIDDK NIH HHS K01 DK114388NIDDK NIH HHS K23 DK115908NIDDK NIH HHS K24 DK101828NIDDK NIH HHS R01 DK096008
6 · The paper itself

Abstract

Simple (Bosniak I) renal cysts are considered acceptable in living kidney donor selection in terms of cancer risk. However, they tend to increase in number and size over time and might compromise renal function in donors. To clarify their implications for long-term renal function, we characterized the prevalence of renal cysts in 454 individuals who donated at our center from 2000 to 2007. We estimated the association between the presence of cysts in the kidney remaining after nephrectomy (ie, retained cysts) and postdonation eGFR trajectory using mixed-effects linear regression. Donors with retained cysts (N = 86) were older (P < .001) and had slightly lower predonation eGFR (median 94 vs 98 mL/min/1.73 m

Indexed as

CystsKidney Diseases, CysticKidney Failure, ChronicKidney TransplantationGlomerular Filtration RateHumansKidneyLiving DonorsNephrectomyRetrospective Studiesdonors and donationglomerular filtration ratelivingrenal cystrenal function

Identifiers

PMID32399996
PMCPMC8720490
OpenAlexW3025820402

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.