ArticleEuropean child & adolescent psychiatry2021
Is an irritable ADHD profile traceable using personality dimensions? Replicability, stability, and predictive value over time of data-driven profiles.
Article in European child & adolescent psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- The Evolving ADHD Phenotype in the Externalizing Context.The American journal of psychiatry · 2026Review
- Finding Similarities in Differences Between Autistic Adults: Two Replicated Subgroups.Journal of autism and developmental disorders · 2024Article
- Clinical subtyping using community detection: Limited utility?International journal of methods in psychiatric research · 2023Article
- Mental health in Canadian children and adolescents during COVID-19 pandemic: the role of personality and, coping and stress responses.Frontiers in psychology · 2023Article
- Diagnostic overlap and exploration of risk factors in child psychiatry.European child & adolescent psychiatry · 2021Article
- Subgroups in Late Adulthood Are Associated With Cognition and Wellbeing Later in Life.Frontiers in psychology · 2021Article
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
Pediatric attention deficit/hyperactivity disorder (ADHD) is a heterogeneous condition. In particular, children with ADHD display varying profiles of dispositional traits, as assessed through temperament and personality questionnaires. Previous data-driven community detection analyses based on temperament dimensions identified an irritable profile of patients with ADHD, uniquely characterized by elevated emotional dysregulation symptoms. Belonging to this profile increased the risk of developing comorbid disorders. Here, we investigated whether we could replicate this profile in a sample of 178 children with ADHD, using community detection based on personality dimensions. Stability of the identified profiles, of individual classifications, and clinical prediction were longitudinally assessed over a 1-year interval. Three personality profiles were detected: The first two profiles had high levels of neuroticism, with the first displaying higher ADHD severity and lower openness to experience (profile 1; N = 38), and the second lower agreeableness (profile 2; N = 73). The third profile displayed scores closer to the normative range on all five factors (profile 3; N = 67). The identified profiles did only partially replicate the temperament-based profiles previously reported, as higher levels of neuroticism were found in two of the three detected profiles. Nonetheless, despite changes in individual classifications, the profiles themselves were highly stable over time and of clinical predictive value. Whereas children belonging to profiles 1 and 2 benefited from starting medication, children in profile 3 did not. Hence, belonging to an emotionally dysregulated profile at baseline predicted the effect of medication at follow-up over and above initial ADHD symptom severity. This finding suggests that personality profiles could play a role in predicting treatment response in ADHD.
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