Evidence map›Paper›PMID 32399786›Full record

ArticleThe ultrasound journal2020

Ultrasound measurement of optic nerve sheath diameter pre- and post-lumbar puncture.

Christopher K Schott, Mohammad I Hirzallah, Rock Heyman, Daniel N Lesky, Emily B Brant, Clifton W Callaway

Open access · goldAbstract read
In one paragraph

Article in The ultrasound journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Christopher K SchottVA Pittsburgh Health Care Systems * Critical Care Service Line (124U), University Drive, Pittsburgh, PA, 15240, USA. Christopher.Schott@va.gov.ORCID http://orcid.org/0000-0002-7467-3158
Mohammad I HirzallahUniversity of Pittsburgh Multidisciplinary Critical Care Training Program, 3550 Terrace Street Scaife Hall, Suite 600, Pittsburgh, PA, 15213, USA.
Rock HeymanDepartment of Neurology, University of Pittsburgh, and University of Pittsburgh Medical Center (UPMC), 300 Halket Street, Suite 4500, Pittsburgh, PA, USA, 15213.
Daniel N LeskySchool of Medicine 401 Scaife Hall, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA, 15261, USA.
Emily B BrantUniversity of Pittsburgh Multidisciplinary Critical Care Training Program, 3550 Terrace Street Scaife Hall, Suite 600, Pittsburgh, PA, 15213, USA.
Clifton W CallawayDepartment of Emergency Medicine, University of Pittsburgh, and University of Pittsburgh, Medical Center (UPMC), 3600 Forbes at Meyran Avenue Forbes Tower, Suite 10028, Pittsburgh, PA, 15213, USA.
University of Pittsburgh · USUniversity of Pittsburgh Medical Center · USVA Pittsburgh Healthcare System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo test the hypothesis that optic nerve sheath diameter (ONSD) correlates with real-time changes in intracranial pressure, we performed ultrasound measurements of the ONSD in ambulatory patients undergoing elective lumbar puncture (LP). We conducted a prospective cohort study, including adult patients undergoing LP in a non-emergent setting. We measured ONSD perpendicular to the optic nerve at 3 mm behind the globe in both eyes in the traverse and sagittal planes, with the patient supine. The primary outcome was change in ONSD from pre-LP to post-LP. We calculated association of opening and closing LP pressures with changes in the pre- and post-LP ONSD measurements.

resultsThe mean patient age was 49.0 years (SD = 37-61, range 19-67) with 21 females (72.4%) and 26 (89.7%) white American (not Hispanic or Latino). The average opening pressure and closing pressures were 20.4 cm and 13.5 cm with a difference of 6.9 cm, (95% CI 3.9-10.0 cm). Pressures between the participants with baseline ONSD measurement > 5 mm (average opening pressure = 21.3 cm) to those < 5 mm (20.2 cm) differed by 1.1 cm (95% CI - 5.7 to 8.0). Linear regression revealed no association between the sagittal, transverse, average, and change in ONSD measurements with the observed LP opening pressure, change in LP pressure, or volume of cerebral spinal fluid (CSF) drained.

conclusionsIn this study of ambulatory patients undergoing rapid decreases in ICP via elective LP, we detected no acute changes in ultrasonographic measurement of the ONSD.

Indexed as

Intracranial pressureOptic nerve sheath diameterUltrasound

Identifiers

PMID32399786
PMCPMC7218034
OpenAlexW3026043418

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.