ArticleParasitology research2020
The anticoccidial activity of the fluoroquinolone lomefloxacin against experimental Eimeria tenella infection in broiler chickens.
Article in Parasitology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- The global prevalence and associated risk factors of Eimeria infection in domestic chickens: A systematic review and meta-analysis.Veterinary medicine and science · 2024Pooled it
- Preventive and therapeutic efficacy of a pyrazole-modified chitosan Schiff base-iron nanocomposite againstVeterinary world · 2025Article
- Eukaryotic gut community of the batPeerJ · 2025Article
- Therapeutic impact of dietary ginger supplementation in chickens experimentally infected with coccidia-anti-oxidant, biochemical, and pathological evaluations.Frontiers in veterinary science · 2025Article
- Efficacy and safety of diclazuril nanoemulsion in control of Eimeria tenella in broilers.BMC veterinary research · 2024Article
- Effects of prebiotic (lactoferrin) and diclazuril on broiler chickens experimentally infected withFrontiers in veterinary science · 2024Article
- Comparative study between chemical anticoccidial medication and natural prepared products on experimentally infected broiler chickens.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023Article
- Effects of Chlorogenic Acid on Performance, Anticoccidial Indicators, Immunity, Antioxidant Status, and Intestinal Barrier Function in Coccidia-Infected Broilers.Animals : an open access journal from MDPI · 2022Article
- Dietary Cinnamon Bark Affects Growth Performance, Carcass Characteristics, and Breast Meat Quality in Broiler Infected withAnimals : an open access journal from MDPI · 2022Article
- Use of Zinc Oxide Nanoparticles as Anticoccidial Agents in Broiler Chickens along with Its Impact on Growth Performance, Antioxidant Status and Hematobiochemical Profile.Life (Basel, Switzerland) · 2022Article
- Article
- Effect ofAnimals : an open access journal from MDPI · 2021Article
- Comparative effect of papaya (Journal of advanced veterinary and animal research · 2021Article
- S-Methylcysteine Ameliorates the Intestinal Damage Induced byFrontiers in veterinary science · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coccidiosis is a crucial parasitic disease of the poultry industry. As a result of the enormous global economic losses and the increased resistance to the conventional anticoccidial agents, there is a continuous need to find new anticoccidials. Here, the anticoccidial effect of the fluoroquinolone lomefloxacin versus diclazuril in experimentally infected broilers was tested for the treatment of Eimeria tenella infection. Ninety 14-day-old Cobb strain broiler chickens were allocated into five groups, each with 18 chicks. Group 1 (G1) was separated as an uninfected negative control and received no treatment; group 2 (G2), infected untreated (positive control); group 3 (G3), infected and treated with lomefloxacin at a dose rate of 100 ppm in drinking water; group 4 (G4), infected and treated with diclazuril at a dose rate of 2.5 ppm in drinking water; group 5 (G5), infected and treated with lomefloxacin at a dose rate of 100 ppm plus diclazuril at dose rate of 2.5 ppm in drinking water. Clinical signs, mortality rates, number of oocysts per gram of faeces (OPG), growth performance parameters (weight gain: WG and feed conversion ratio: FCR), lesion scoring, haematological and serum biochemical analyses, antioxidant biomarkers and histopathologic inspection of the caeca were used as evaluation criteria for the anticoccidial efficacy of both lomefloxacin and diclazuril. The findings herein showed that administration of lomefloxacin and/or diclazuril improved growth performance parameters (WG, FCR) and significantly (P ≤ 0.05) reduced OPG, and diminished the severity of bloody diarrhoea and mortalities. Additionally, haematological indices and serum biochemical parameters such as ALT, AST, ALP, creatinine, uric acid, total proteins, albumin and globulin were improved. Finally, a significant elevation in the levels of the antioxidant biomarkers was observed in the chicks of G3, G4 and G5 as compared with those of G2.
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