Evidence map›Paper›PMID 32399710›Full record

ArticleEuropean radiology2020

COVID-19 pneumonia: CT findings of 122 patients and differentiation from influenza pneumonia.

Mengqi Liu, Wenbin Zeng, Yun Wen, Yineng Zheng, Fajin Lv, Kaihu Xiao

2 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 71 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 4 pooled it
3.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04497311 unknown statusnot on this map

Pulmonary Tomographic Findings in COVID-19 and Influenza H1N1 Patients

TypeobservationalSponsorUniversidad de GuanajuatoRan2020 to 2022Enrolled100ConditionsSARS-CoV-2, Covid19, H1N1 Influenza, Computed TomographyArmsThoraxic computed tomography
NCT04499378 unknown statusnot on this map

Pulmonary Tomographic Findings in COVID-19 and Influenza H1N1 Patients at IMSS Guanajuato

TypeobservationalSponsorUniversidad de GuanajuatoRan2020 to 2022Enrolled200ConditionsCovid19, Influenza A H1N1, Intubation Complication, MoralityArmsLung CT
3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 4 syntheses or guidelines pooled it, 137 citations in OpenAlex.

  1. Pooled it
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  5. Expert consensus on imaging diagnosis of human infection with avian influenza.Quantitative imaging in medicine and surgery · 2026
    Review
  6. Subsegmental vascular dilatations: An important finding in COVID-19 pneumonia.Revista da Sociedade Brasileira de Medicina Tropical · 2026
    Article
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mengqi LiuDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Wenbin ZengMedical Imaging Center, Chongqing Three Gorges Central Hospital, Chongqing, 404100, China.
Yun WenMedical Imaging Center, Chongqing Three Gorges Central Hospital, Chongqing, 404100, China.
Yineng ZhengDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Fajin LvDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. fajinlv@163.com.
Kaihu XiaoDepartment of Cardiology, Chongqing Three Gorges Central Hospital, Chongqing, 404100, China. xiaokh1@163.com.ORCID http://orcid.org/0000-0003-3768-2562
Chongqing Three Gorges Central Hospital · CNThe Affiliated Yongchuan Hospital of Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the clinical and chest CT characteristics of COVID-19 pneumonia and explore the radiological differences between COVID-19 and influenza. MATERIALS AND

methodsA total of 122 patients (61 men and 61 women, 48 ± 15 years) confirmed with COVID-19 and 48 patients (23 men and 25 women, 47 ± 19 years) confirmed with influenza were enrolled in the study. Thin-section CT was performed. The clinical data and the chest CT findings were recorded.

resultsThe most common symptoms of COVID-19 were fever (74%) and cough (63%), and 102 patients (83%) had Wuhan contact. Pneumonia in 50 patients with COVID-19 (45%) distributed in the peripheral regions of the lung, while it showed mixed distribution in 26 patients (74%) with influenza (p = 0.022). The most common CT features of the COVID-19 group were pure ground-glass opacities (GGO, 36%), GGO with consolidation (51%), rounded opacities (35%), linear opacities (64%), bronchiolar wall thickening (49%), and interlobular septal thickening (66%). Compared with the influenza group, the COVID-19 group was more likely to have rounded opacities (35% vs. 17%, p = 0.048) and interlobular septal thickening (66% vs. 43%, p = 0.014), but less likely to have nodules (28% vs. 71%, p < 0.001), tree-in-bud sign (9% vs. 40%, p < 0.001), and pleural effusion (6% vs. 31%, p < 0.001).

conclusionsThere are significant differences in the CT manifestations of patients with COVID-19 and influenza. Presence of rounded opacities and interlobular septal thickening, with the absence of nodules and tree-in-bud sign, and with the typical peripheral distribution, may help us differentiate COVID-19 from influenza. KEY POINTS: • Typical CT features of COVID-19 include pure ground-glass opacities (GGO), GGO with consolidation, rounded opacities, bronchiolar wall thickening, interlobular septal thickening, and a peripheral distribution. • Presence of rounded opacities and interlobular septal thickening, with the absence of nodules and tree-in-bud sign, and with the typical peripheral distribution, may help us differentiate COVID-19 from influenza.

Indexed as

BetacoronavirusAdolescentAdultAgedAged, 80 and overCoronavirus InfectionsCOVID-19Diagnosis, DifferentialFemaleHumansInfluenza, HumanLungMaleMiddle AgedPandemicsPneumonia, ViralCoronavirus infectionsHumanInfluenzaPneumonia, viralTomography, x-ray computed

Identifiers

PMID32399710
PMCPMC7216854
OpenAlexW3024709086

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.