Evidence map›Paper›PMID 32399676›Full record

ArticleJournal of bone and mineral metabolism2020

Long-term excess mortality after hip fracture in hemodialysis patients: a nationwide cohort study in Japan.

Minako Wakasugi, Junichiro James Kazama, Atsushi Wada, Takayuki Hamano, Ikuto Masakane, Ichiei Narita

Abstract read
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In one paragraph

Article in Journal of bone and mineral metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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  9. Authors' reply.Journal of bone and mineral metabolism · 2022
    Article
  10. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Minako WakasugiDivision of Comprehensive Geriatrics in Community, Niigata University Graduate School of Medical and Dental Sciences, Asahimachi 1-757, Chuo-ku, Niigata, 951-8510, Japan. minakowa@med.niigata-u.ac.jp.
Junichiro James KazamaDepartments of Nephrology and Hypertension, Fukushima Medical University, Fukushima, Japan.
Atsushi WadaCommittee of Renal Data Registry, Japanese Society for Dialysis Therapy, Tokyo, Japan.
Takayuki HamanoCommittee of Renal Data Registry, Japanese Society for Dialysis Therapy, Tokyo, Japan.
Ikuto MasakaneCommittee of Renal Data Registry, Japanese Society for Dialysis Therapy, Tokyo, Japan.
Ichiei NaritaDivision of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Science, Niigata, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFracture dialysis patients have a higher risk of 1-year mortality compared with non-fracture dialysis patients. However, it is unclear whether excess mortality persists for more than a year. MATERIALS AND

methodsWe conducted a nationwide cohort study in 162,360 hemodialysis patients in Japan. Study outcomes were 5-year all-cause mortality and cause-specific mortality. Cox proportional hazards regression was used to examine the association between hip fracture and mortality in two cohorts: the full cohort, which included potential confounders as covariates in multivariable-adjusted regression models, and the propensity score-matched cohort.

resultsCrude mortality rates for fracture patients were double those of non-fracture patients and persisted during the 5-year period. The association between hip fracture and mortality was significant even after adjusting for premorbid conditions (hazard ratio (HR) 1.22, 95% confidence interval (CI) 1.13-1.32). Similar findings were observed in the propensity score-matched cohort of 2410 patients (HR 1.20, 95% CI 1.05-1.36). While cause-specific mortality rates for all categories, with the exception of sudden deaths, were higher for fracture patients relative to non-fracture patients in the full unmatched cohort, only the mortality rate for heart disease was significantly higher for fracture patients relative to non-fracture patients in the propensity score-matched cohort.

conclusionExcess mortality persisted for many years after hip fracture in hemodialysis patients, and was still present after adjusting for several premorbid conditions and propensity score matching.

Indexed as

AgedCause of DeathCohort StudiesFemaleHip FracturesHumansJapanKaplan-Meier EstimateMalePropensity ScoreProportional Hazards ModelsRenal DialysisCardiovascularDialysisEnd-stage kidney diseaseHip fractureMortality risk

Identifiers

PMID32399676

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.