Evidence map›Paper›PMID 32399664›Full record

ArticleEJNMMI physics2020

Optimization of [

Elin Trägårdh, David Minarik, Gustav Brolin, Ulrika Bitzén, Berit Olsson, Jenny Oddstig

Open access · goldAbstract read
In one paragraph

Article in EJNMMI physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. β1600 Q.Clear Digital Reconstruction of [Journal of clinical medicine · 2024
    Article
  4. [European journal of hybrid imaging · 2023
    Article
  5. PET/CT imaging 2 h after injection of [European journal of hybrid imaging · 2023
    Article
  6. [Clinical physiology and functional imaging · 2023
    Article
  7. Article
  8. Biokinetics and dosimetry ofClinical physiology and functional imaging · 2022
    Article
  9. Assessing the accuracy of [EJNMMI research · 2022
    Article
  10. Article
  11. Influences on PET Quantification and Interpretation.Diagnostics (Basel, Switzerland) · 2022
    Review
  12. Article
  13. Dose-reduced [EJNMMI physics · 2021
    Article
  14. Moving the goalposts while scoring-the dilemma posed by new PET technologies.European journal of nuclear medicine and molecular imaging · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Elin TrägårdhClinical Physiology and Nuclear Medicine, Skåne University Hospital and Lund University, Carl Bertil Laurells gata 9, 205 02, Malmö, Sweden. elin.tragardh@med.lu.se.ORCID http://orcid.org/0000-0002-7116-303X
David MinarikWallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden.
Gustav BrolinWallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden.
Ulrika BitzénClinical Physiology and Nuclear Medicine, Skåne University and Lund University, Lund, Sweden.
Berit OlssonClinical Physiology and Nuclear Medicine, Skåne University and Lund University, Lund, Sweden.
Jenny OddstigWallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden.
Lund University · SE

Funding

Knut och Alice Wallenbergs Stiftelse -Medicinska Fakulteten, Lunds Universitet -Prostatacancerförbundet -Region Skåne -
6 · The paper itself

Abstract

backgroundProstate-specific membrane antigen (PSMA) radiotracers such as [

resultsThe noise level in the liver, spleen, and muscle was higher for low β values and low acquisition times (written as activity time products (ATs = administered activity × acquisition time)) and was minimized at maximum AT (16 MBq/kg min) and maximum β (1400). There was only a small decrease above AT 10. The median CNR increased slowly with AT from approximately 6 to 12 and was substantially lower at AT 4 and higher at AT 14-16. At AT 4-6, many images were regarded as being of unacceptable quality. For AT 8, β values of 700-900 were considered of acceptable quality.

conclusionsAn AT of 8 (for example as in our study, 4 MB/kg with an acquisition time of 2 min) with a β value of 700 performs well regarding noise level, CNR, and visual image quality assessment.

Indexed as

[18F]PSMA-1007Block-sequential regularized expectation maximizationImage qualityPET-CTPSMAQ.Clear

Identifiers

PMID32399664
PMCPMC7218038
OpenAlexW3027957804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.