Evidence map›Paper›PMID 32399602›Full record

ArticleJapanese journal of radiology2020

Usefulness of deep learning-assisted identification of hyperdense MCA sign in acute ischemic stroke: comparison with readers' performance.

Yuki Shinohara, Noriyuki Takahashi, Yongbum Lee, Tomomi Ohmura, Atsushi Umetsu, Fumiko Kinoshita, Keita Kuya, Ayumi Kato, Toshibumi Kinoshita

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Japanese journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Acute ischemic stroke patient factors associated with poor outcomes in patients with favorable collaterals and successful thrombectomy.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Vessel wall MR imaging in neuroradiology.La Radiologia medica · 2022
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Yuki ShinoharaDepartment of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels-Akita, 6-10 Senshu-kubota-machi, Akita, 010-0874, Japan. shino-y@akita-noken.jp.ORCID http://orcid.org/0000-0001-6586-4086
Noriyuki TakahashiDepartment of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels-Akita, 6-10 Senshu-kubota-machi, Akita, 010-0874, Japan.
Yongbum LeeGraduate School of Health Science, Niigata University, Niigata, Japan.
Tomomi OhmuraDepartment of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels-Akita, 6-10 Senshu-kubota-machi, Akita, 010-0874, Japan.
Atsushi UmetsuDepartment of Diagnostic Radiology, Tohoku University School of Medicine, Sendai, Japan.
Fumiko KinoshitaDepartment of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels-Akita, 6-10 Senshu-kubota-machi, Akita, 010-0874, Japan.
Keita KuyaDepartment of Radiology, Secomedic Hospital, Funabashi, Japan.
Ayumi KatoDivision of Radiology, Department of Pathophysiological Therapeutic Science, Faculty of Medicine, Tottori University, Yonago, Japan.
Toshibumi KinoshitaDepartment of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels-Akita, 6-10 Senshu-kubota-machi, Akita, 010-0874, Japan.
Research Institute for Brain and Blood Vessels Akita · JPFukushima Medical University · JPFunabashi Orthopaedic Hospital · JPNiigata University · JPTohoku University · JPTottori University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the usefulness of deep learning-assisted diagnosis for identifying hyperdense middle cerebral artery sign (HMCAS) on non-contrast computed tomography in comparison with the diagnostic performance of neuroradiologists. MATERIALS AND

methodsWe obtained 46 HMCAS-positive and 52 HMCAS-negative test samples extracted using 50-pixel-diameter circular regions of interest. Five neuroradiologists undertook an initial diagnostic performance test by describing the HMCAS-positive prediction rate in each sample. Their diagnostic performance was compared with that of a deep convolutional neural network (DCNN) model that had been trained using another dataset in our previous study. In the second test, readers could reference the prediction rate of the DCNN model in each sample.

resultsThe diagnostic performance of the DCNN for HMCAS showed an accuracy of 81.6% and area under the receiver-operating characteristic curve (AUC) of 0.869, whereas the initial diagnostic performance of neuroradiologists showed an accuracy of 78.8% and AUC of 0.882. The second diagnostic test of neuroradiologists with reference to the results of the DCNN model showed an accuracy of 84.7% and AUC of 0.932. In all readers, AUC values were higher in the second test than the initial test.

conclusionThe ability of DCNN to identify HMCAS is comparable with the diagnostic performance of neuroradiologists.

Indexed as

Deep LearningAgedAged, 80 and overBrain IschemiaFemaleHumansImage Interpretation, Computer-AssistedIschemic StrokeMaleMiddle AgedMiddle Cerebral ArteryRetrospective StudiesROC CurveTomography, X-Ray ComputedAcute ischemic strokeDeep learningHyperdense artery signHyperdense MCA signNon-contrast CT

Identifiers

PMID32399602
OpenAlexW3025727832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.