Evidence map›Paper›PMID 32399146›Full record

ReviewIndian journal of orthopaedics2020

Neuroplasticity and Anterior Cruciate Ligament Injury.

George Kakavas, Nikolaos Malliaropoulos, Ricard Pruna, David Traster, Georgios Bikos, Nicola Maffulli

Abstract readReview
In one paragraph

Review in Indian journal of orthopaedics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. Neurophysiology of ACL Injury.Orthopedic reviews · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

George KakavasFysiotek Spine & Sports Lab, Athens, Greece.
Nikolaos MalliaropoulosThessaloniki MSK Sports Medicine Clinic, Thessaloniki, Greece.ORCID 0000-0002-5327-3702
Ricard Pruna4FC Barcelona, FIFA Medical Center of Excellence, St Joan Despi, Barcelona, Spain.
David Traster5Carrick Institute of Neurology, Cape Canaveral, FL USA.
Georgios BikosEuromedica Arogi Rehabilitation Center, Thessaloniki, Greece.
Nicola Maffulli3Queen Mary University of London, Centre for Sports and Exercise Medicine, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAnterior cruciate ligament (ACL) tears are common, with a seemingly constant increase in their number, and potentially serious consequences for sports participation and long-term general and musculoskeletal health. AREAS OF AGREEMENT: Most players are able to return to cutting sport after ACL reconstruction, but some sustain further knee problems needing different approach to their rehabilitation. GROWING POINTS: Neurocognitive tasks, measuring reaction time, processing speed, visual memory and verbal memory, allow indirect assessment of cerebral performance. Situational awareness, arousal, and attentional resources may influence neurocognitive function, affecting the complex integration of vestibular, visual, and somatosensory information needed for neuromuscular control. AREAS OF CONTROVERSY: The underlying reasons for uncoordinated, high-velocity movements observed during non-contact injuries of the knee producing an ACL tear are not well understood. Fundamental neuropsychological characteristics are responsible for situational awareness, sensory integration, motor planning, and coordination, all of which control joint stiffness. There is a strong link between acquisition of motor skills and neuronal plasticity at cortical and subcortical levels in the central nervous system; these links may evolve over time and engage different spatially distributed interconnected brain regions. A cascade of neurophysiological alterations occurs after ACL injury. AREAS TIMELY FOR DEVELOPING RESEARCH: Training can improve function; hence, rehabilitation programmes which include perturbation training, agility training, vision training and sport-specific skill training are essential after ACL injuries and for injury prevention, and to optimize return to play.

Indexed as

Anterior cruciate ligamentInjuryNeuroplasticityRecoveryReturn to playSensory input

Identifiers

PMID32399146
PMCPMC7205971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.